Primesep 200 is a mixed-mode analytical column with weak acidic ion-pairing groups embedded into long ligand chains.

– Enhances retention of strong basic compounds through cation-exchange mechanism.
– Retains neutral compounds by reverse-phase mechanism.
– Provides an additional interaction with polar molecules, enabling separation of isomers and structurally-related compounds.
– Allows for mobile phase selection suitable for LC-MS and preparative chromatography, as well as low UV detection.