Key Benefits:

• ✓
  All-in-One Performance – RP, HILIC, ion-exchange, ion-exclusion, and normal phase in a single column.
• ✓
  Dynamic Adaptation – Surface chemistry responds to solvent composition, buffer, pH, and ionic strength.
• ✓
  Tunable Selectivity – Fine-tune separations with small adjustments in organic content, salt, or pH.
• ✓
  Single-Phase Advantage – No mixed packing or phase separation; ensures reproducible results and robust performance.
• ✓
  Versatile Compatibility – Works with aqueous-organic systems, pure organic solvents, and common mobile phase additives.
• ✓
  Trace-Level Sensitivity – Exceptionally low bleed, suitable for LC-MS and advanced detection methods.

How It Works?

Chromni™’s stationary phase integrates in a single ligand hydrophobic, polar, and ionizable functionalities in a carefully balanced chemistry. This allows one column to switch between separation modes simply by adjusting the mobile phase:

• Aqueous-organic mobile phases → Hydrophobic retention (Reversed-phase)
• High-organic conditions → Polar retention (HILIC)
• Buffered ionic modifiers → Ion-exchange / Ion-exclusion
• Pure organic solvents → Normal phase

The result is unprecedented flexibility and control, enabling laboratories to explore multiple retention mechanisms without changing columns.