Transforming Lipid Analysis with Innovation
Accurate, Reliable, and Simplified
Imagine achieving unparalleled resolution and precision in lipidomics with a single column that accommodates the diverse polarities of lipid species. The Lipak™ column redefines lipid analysis, offering a simplified yet robust solution for separating both polar and nonpolar lipid classes with unmatched efficiency.
The Lipak™ Column: A Breakthrough in Lipid Separations
Traditional chromatographic methods, such as reverse-phase (RP) chromatography, often fall short in separating the vast array of lipid species due to their reliance on single interaction modes. The Lipak™ column integrates mixed-mode chromatography, combining reverse-phase functionality with a negatively charged group in its stationary phase, delivering a dual-mode interaction system that is ideal for lipid analysis.
How the Lipak™ Column Works for Lipids
The Lipak™ method enables:
- Dual Interaction Modes: Retention of both polar and nonpolar lipid species by leveraging reverse-phase and ionic interactions.
- High Organic Mobile Phases: Compatibility with high-organic conditions eliminates solubility issues for fatty molecules, ensuring excellent peak shape and resolution.
- Versatility Across Lipid Classes: From nonpolar triglycerides to dual polarity phospholipids, the Lipak™ column ensures complete and precise separation.
Why Choose the Lipak™ Column?
Simultaneous Separation of Lipid Classes
The Lipak™ column bridges the gap in traditional chromatography by accommodating the diverse chemical structures of lipids. Whether analyzing nonpolar triglycerides or dual polarity phospholipids, the column ensures optimal separation through its dual-mode interaction.
Superior Resolution for Complex Mixtures
Comprehensive lipidomics requires selective identification and quantification of individual lipid species. The Lipak™ column achieves superior resolution, even for challenging lipid mixtures, enabling a deeper understanding of lipid profiles.
Beyond Lipids
The Lipak™ column isn’t limited to lipids. It is equally effective for separating:
- Fat-soluble vitamins
- Chlorophylls
- Surfactants
- And other complex compounds
Separation of Phospholipids Using the Lipak™ Column
Optimized for Your Workflow
The Lipak™ column is available in 5 µm and 3 µm particle sizes and can be customized to fit your analytical requirements. It is compatible with UV, MS, ELSD, and CAD detection methods, making it a versatile tool for diverse analytical platforms.
Separation of Retinol, Retinyl Acetate, and Retinyl Palmitate
Discover More
Experience the revolution in lipidomics with the Lipak™ column. To explore detailed applications and results, visit our brochure or contact us today.
