Chromni
- Description
- Purchase
- Applications
| Column Diameter | 1 mm, 2.1 mm, 3.2 mm, 4.6 mm |
|---|---|
| Column Length | 25 mm, 50 mm, 100 mm, 150 mm, 250 mm |
| Particle Size | 3 µm, 5 µm |
| Pore Size | 100 A |
| Brand | SIELC Technologies |
| Column options | Dual ended |
SIELC Chromni – The All-in-One HPLC Column for Every Separation Mode
Chromni is a revolutionary mixed-mode HPLC column designed to replace multiple specialized columns with one adaptive solution. Traditional chromatography requires separate columns for reversed-phase, HILIC, ion-exchange, ion-exclusion, or normal phase separations. Chromni changes this paradigm by combining all interactions into a single, unified stationary phase.
With its dynamic and responsive surface chemistry, Chromni adapts to the mobile phase conditions — enabling precise control of selectivity and retention for a wide range of analytes. From polar to nonpolar compounds, acidic, basic, or neutral species, Chromni makes method development simpler, faster, and more efficient.
Key Benefits:
- ✓
All-in-One Performance – RP, HILIC, ion-exchange, ion-exclusion, and normal phase in a single column. - ✓
Dynamic Adaptation – Surface chemistry responds to solvent composition, buffer, pH, and ionic strength. - ✓
Tunable Selectivity – Fine-tune separations with small adjustments in organic content, salt, or pH. - ✓
Single-Phase Advantage – No mixed packing or phase separation; ensures reproducible results and robust performance. - ✓
Versatile Compatibility – Works with aqueous-organic systems, pure organic solvents, and common mobile phase additives. - ✓
Trace-Level Sensitivity – Exceptionally low bleed, suitable for LC-MS and advanced detection methods.
How It Works?
Chromni’s stationary phase integrates hydrophobic, polar, and ionizable functionalities in a carefully balanced chemistry. This allows one column to switch between separation modes simply by adjusting the mobile phase:
- Aqueous-organic mobile phases → Hydrophobic retention (Reversed-phase)
- High-organic conditions → Polar retention (HILIC)
- Buffered ionic modifiers → Ion-exchange / Ion-exclusion
- Pure organic solvents → Normal phase
The result is unprecedented flexibility and control, enabling laboratories to explore multiple retention mechanisms without changing columns.
Benefits
SIELC Chromni is an all-in-one HPLC column for RP, HILIC, ion-exchange, and more. Simplify workflows and expand your lab’s capabilities.
36-month financing with market rates is offered to companies, individuals, and educational institutions subject to credit approval. For more details please contact us at financing@sielc.com.
