HPLC Method for Analysis of (+-)-Tetramisole on Primesep NC by SIELC Technologies
Tetramisole is a medication with the chemical formula C11H12N2S. It is primarily used to treat and get rid of parasitic worms in animals. It works through inhibiting alkalinephosphates, which freezes muscles of the worm. You can find detailed UV spectra of (+-)-Tetramisole and information about its various lambda maxima by visiting the following link.
(+-)-Tetramisole can be retained and analyzed using the Primesep 200 stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of acetonitrile, water, and ammonium formate. Detection is performed using MS.
Condition
| Column | Primesep 200, 3.2 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O -40/60% |
| Buffer | AmFm pH 3.0 – 20 mM |
| Flow Rate | 0.5 ml/min |
| Detection | ESI-SIM: [M-H]– m/z 205 |
Description
| Class of Compounds | Drugs |
| Analyzing Compounds | (+-)-Tetramisole |
Application Column
Primesep 200
Column Diameter: 3.2 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Application Analytes:
(+-)-TetramisoleApplication Detection:
LC MS Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.
