Use this tool to narrow down your Primesep column selection by your analyte’s properties.
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BIST™ – a New Mode of LC Separation
Bridge Ion Separation Technology, or BIST™, is a brand new LC separation technique developed by SIELC. The goal of BIST™ is simple – expand the scope of HPLC applications.
BIST™ from SIELC Technologies is a new and simple way to achieve many separations that are traditionally difficult or impossible to achieve with any other HPLC columns currently on the market! In short, BIST™ is complex chromatography without the hassle.
BIST™ provides an additional separation tool for a whole class of organic and inorganic charged molecules. BIST™ columns, simple mobile phases, and an array of applications provide a whole new continent on the chromatography map.
SIELC Technologies offers several innovative HPLC Systems & devices often used in chromatography applications to add special capabilities. These devices include:
→ The Alltesta™ Analyzer
→ The Cromite™ Analyzer
→ The Samplify™ System
→ High Pressure Switching Valve
→ HPLC Syringe & Binary Pump
→ OEM Autosampler
→ UV-Vis Detector
Samples from natural sources, such as fruits, vegetables, culinary products, water, soil, and bodily fluids, are complex mixtures containing dozens, or even hundreds, of compounds. Our FlipLC method removes impurities from these complex samples, shortens chromatography run time, and increases the column lifetime. It requires minimal sample preparation. The isolation column flips direction and position in the flow path during this process, and thus we have the name FlipLC.
Newcrom is an advanced column format with a new inner/outer design. This column and the corresponding adapter entirely eliminate the need for any high-pressure fittings or tubing, as well as minimizing all possible dead volumes. Furthermore, if a leak ever occurs in the high-pressure column inlet, the mobile phase is contained within the column adapter (no external leakage). Read more.
SHARC™ HPLC columns are the latest innovative columns from SIELC Technologies, the inventors of Primesep®. SHARC™ columns are the first commercially available columns with separation based primarily on hydrogen bonding. SHARC stands for Specific Hydrogen-bond Adsorption Resolution Column. Hydrogen bonding is an interaction (attraction) between hydrogen atoms bonded to an electronegative atom (i.e. oxygen, nitrogen, fluorine) and similarly electronegative atoms on different molecules.
Primesep stationary phases offer unprecedented selectivity in the separation of a broad array of chemical compounds, and in multiple applications. A wide range of HPLC columns with I.D.’s from 0.5 mm to 22 mm are available. Corresponding Primesep guard columns are available for all stationary phases and do not require holders. SIELC offers a method development service which is available for all customers. Ask about our special custom HPLC phases tailored for specific separations.
Two complimentary columns, Obelisc R and Obelisc N, based on Liquid Separation Cell ( LiSC ™) technology, offer a new approach to separate a variety of small molecules. Buffer concentration, buffer pH, and organic modifier concentration are three orthogonal parameters of the mobile phase that allow adjustment of column properties to separate complex mixtures.
Promix is an alternative chromatography technology for efficient resolution of peptides and proteins. The technology is based on a combination of two interactions – hydrophobic and ionic. This approach is possible due to a new type of separation medium: a chemical combination of hydrophobic and ionic functional groups, on a ligand bonded to a silica support. With this phase, unparalleled selectivity and peak capacity can be achieved. Independent adjustment of the amount of buffer and organic modifier creates an infinite number of separation conditions, that are suitable for many types of bio-molecules.
SIELC offers “Legacy” columns. These columns support historical and current USP-validated methods.
Four types of USP Specifications are offered: Legacy L1, Legacy L3, Legacy L8, Legacy L16.
- SIELC Technologies offers a patented design of capillary, analytical, and preparative hardware for HPLC.
- Unified cylindrical shape of the columns is a signature hardware style developed and produced by SIELC.
- Superior performance, distinguished look, and reduced hardware costs are just a few benefits of the new design.
SIELC offers an innovative new design of fittings for HPLC. This sophisticated new design combines reduced costs with attractive appearance and premium performance. Two versions of fitting are available: (1) for high pressure applications up to 5000 psi (350 bar), (2) for ultrahigh pressure applications up to 14000 psi (1000 bar). Benefits of SIELC fittings include: finger-tight installation, break-resistance, fully metal threads, improved heat transfer, one-size-fits-most applications, several color options, and more.
