Newsletter

SIELC presents the Alltesta™ LHS (Liquid Handling Station)

Posted on May 12, 2023
Tags:
SIELC Technologies is happy to announce the newest addition to our Alltesta™ lab equipment line – the Alltesta LHS (Liquid Handling Station). The Alltesta™ Mini Liquid Handling Station is an affordable and reliable solution for automated sample handling. Featuring a compact design, a proprietary alpha/beta mechanical structure, and adjustable operation speeds, it provides comprehensive control...Read more

Preparative Chromatography As a Service

Posted on May 4, 2023
Tags:
We are excited to offer our clients expanded capabilities in preparative HPLC separation and purification. Our proficiency in chromatography has enabled us to produce unique analytical chromatographic columns and confidentially help our clients achieve their commercial and research goals. Our expertise is employed in research-scale preparative chromatographic applications, such as separating isomers and oligomers including oligonucleotides,...Read more

Oligonucleotides Analysis by HPLC

Posted on April 20, 2023
Tags:
Please see our newest publication on Oligonucleotides analysis by HPLC. We recently reported a new mode of chromatography which we named Bridge Ion Separation Technique (BIST™). This technique was developed in order to obtain better separation control when working with multicharged molecules. Oligonucleotides are exactly the type of molecules that can be separated by this...Read more

SIELC presents the new Alltesta™ Cromite Analyzer

Posted on April 5, 2023
Tags:
The Cromite™ Analyzer represents a new generation of affordable and easy-to-learn HPLC instrumentation for schools, colleges and universities. With automated single-vial injection, high-pressure flow and UV/Vis detection capabilities, scholars can use this instrument to separate compounds, such as vitamins in juices, food dyes, caffeine and active ingredients in pharmaceutical products. The free cloud-connected software allows...Read more

PEI: New Methods and Updated Brochure

Posted on February 2, 2023
Tags:
Many customers have come to us with difficulties in analyzing Polyethylenimine (PEI). It is not a simple polymer to analyze with HPLC for a variety of reasons, including: – PEI is a mixture of different molecules with a large variety of differing lengths and branching structures– PEI has multiple charges in acidic and neutral pH...Read more

Our New Online Shop, HPLC Methods Library updated

Posted on January 12, 2023
Tags:
Dear colleagues! Welcome to our new online store at https://sielc.com/shop! We also have reconstructed our Online Applications Library to make searching simpler and quicker to help you find the method for your compound(s) of interest. If you can’t find the compound that you’re interested in analyzing in our Library, feel free to reach our R&D Lead Brad Widawer at research@sielc.com, and...Read more

Introduction into HPLC and the Primesep Mixed-mode Stationary Phases with Example Applications (video)

Posted on December 13, 2022
Tags:
An introduction to High Pressure/Performance Liquid Chromatography (HPLC), column stationary phases for HPLC, and mixed-mode stationary phases for HPLC with examples of separations of complex mixtures of molecules of interest using the novel Primesep stationary phase column series.

Introduction to Newcrom Mixed-mode Stationary Phases with Example Applications (video)

Posted on December 13, 2022
Tags:
An introduction to the novel Newcrom mixed-mode stationary phase column series with examples of separations of many different compounds of interest.

Bridge Ion Separation Technology-enabled Separation of Food Dyes (video)

Posted on December 13, 2022
Tags:
A series of experiments separating food dyes and other coloring pigments using High Pressure/Performance Liquid Chromatography (HPLC) and the novel chromatographic method Bridge Ion Separation Technology (BIST).

Ion Exchange Separation, BIST™, & other Ionic Interactions with a Charged Surface in an HPLC Column (video)

Posted on December 12, 2022
Tags:
Visual representation of Ion Exchange Separation, Bridge Ion Separation Technology (BIST™), and other possible ion interactions in a charged HPLC column. 1) Ion Exchange Separation (Single-Charged Ions in an Aqueous MP): The surface has a net-positive charge, and retains the single-charged negative ions. The glow around the ions represents the solvation layer that forms around...Read more