Sunset Yellow (Yellow 6)

Sunset Yellow structural formula

CAS Number2783-94-0
Molecular FormulaC16H10N2Na2O7S2
Molecular Weight452.360
InChI KeyOIQPTROHQCGFEF-QIKYXUGXSA-L
LogP0.858
Synonyms
  • FD&C Yellow 6
  • Disodium 6-hydroxy-5-[(E)-(4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
  • 2-Naphthalenesulfonic acid, 6-hydroxy-5-[(E)-2-(4-sulfophenyl)diazenyl]-, sodium salt (1:2)
  • 2783-94-0
  • C.I. 15985
  • C.I. Food Yellow 3
  • 2-Naphthalenesulfonic acid, 6-hydroxy-5-[(4-sulfophenyl)azo]-, disodium salt
  • 1351 Yellow
  • 1899 Yellow
  • 1-p-Sulfophenylazo-2-hydroxynaphthalene-6-sulfonate disodium salt
  • 2-Naphthalenesulfonic acid, 6-hydroxy-5-[2-(4-sulfophenyl)diazenyl]-, sodium salt (1:2)
  • 6-hidroxi-5-[(4-sulfonatofenil)azo]naftaleno-2-sulfonato de disodio
  • 6-Hydroxy-5-(4-sulfonatophenylazo)naphtalene-2-sulfonate de disodium
  • 6-hydroxy-5-[(4-sulfonatophenyl)azo]naphtalene-2-sulfonate de disodium
  • Acid Food Yellow 3
  • Acid Yellow TRA
  • Aizen Food Yellow 5
  • Alabaster No. 3
  • Atul Sunset Yellow FCF
  • C Orange 10
  • C.I. Food Yellow 3, disodium salt
  • Canacert Sunset Yellow FCF
  • Certicol Sunset Yellow CFS
  • Cilefa Orange S
  • Cogilor Orange 213.11
  • D and C Yellow No. 6
  • DC Yellow 6
  • Dinatrium-6-hydroxy-5-[(4-sulfonatophenyl)azo]naphthalin-2-sulfonat
  • Disodium 6-hydroxy-5-[(4-sulfonatophenyl)azo]naphthalene 2-sulfonate
  • disodium 6-hydroxy-5-[(4-sulphonatophenyl)azo]naphthalene-2-sulphonate
  • Dolkwal Sunset Yellow
  • Edicol Supra Yellow FC
  • Eniacid Sunset Yellow
  • Eurocert Orange FCF
  • FD & C Yellow 6
  • FD and C Yellow 6
  • FD AND C YELLOW NO. 6
  • FD&C Yellow No.6
  • Food Yellow 3
  • Food Yellow 5
  • Food Yellow No. 5
  • HD Sunset Yellow FCF
  • HD Sunset Yellow FCF Supra
  • Hexacol Sunset Yellow FCF
  • Hexacol Sunset Yellow FCF Supra
  • KCA Foodcol Sunset Yellow FCF
  • L Orange Z 2010
  • Maple Sunset Yellow FCF
  • NAPHTH-2-OL-6-SULFONATE, 1-(4-SULFO-1-PHENYLAZO)-,DISODIUM
  • Orange II R
  • Orange PAL
  • Orange Yellow 85
  • Orange Yellow S
  • Orange Yellow SFQ
  • Orient Water Yellow 2
  • Para Orange
  • Sun Orange A Geigy
  • Sun Yellow
  • Sun Yellow FCF
  • Sunlight Yellow FCF
  • Sunset Yellow
  • Sunset Yellow 6
  • SUNSET YELLOW FCF
  • Twilight yellow
  • Usacert Yellow No. 6
  • Vitasyn Orange RGL 90
  • Water Yellow 2
  • Yellow No. 6
  • Yellow Orange S
  • Yellow S
  • Yellow Sun
  • Yellow SY
  • D and C Yellow 6
  • L. Orange Z2010
  • A.F. Yellow No. 5
  • Aizen Food Yellow No. 5
  • Disodium 6-hydroxy-5-((4-sulfophenyl)azo)-2-naphthalenesulfonate
  • Disodium salt of 1-p-sulphophenylazo-2-naphthol-6-sulphonic acid
  • Dye FDC Yellow No. 6
  • Dye Sunset Yellow
  • EINECS 220-491-7
  • FD and C No. 6
  • 6-Hydroxy-5-((p-sulfophenyl)azo)-2-naphthalenesulfonic acid, disodium salt
  • 6-Hydroxy-5-((p-sulphophenyl)azo)-2-naphthalenesulphonic acid, disodium salt
  • 6-Hydroxy-5-((4-sulphophenyl)azo)-2-naphthalenesulphonic acid, disodium salt
  • 2-Naphthalenesulfonic acid, 6-hydroxy-5-((4-sulfophenyl)azo)-, disodiumsalt
  • NCI-C53907
  • Orange Yellow S. AF
  • Orange Yellow S. FQ
  • Orange Yellow S.fq
  • Solar radiation color
  • Standacol Sunset Yellow FCF
  • 1-p-Sulfophenylazo-2-hydroxynaphthalene-6-sulfonate, disodium salt
  • 1-p-Sulfophenylazo-2-naphthol-6-sulfonic acid, disodium salt
  • 1-p-Sulphophenylazo-2-naphthol-6-sulphonic acid, disodium salt
  • SUN Yellow A-CE
  • SUN Yellow Extra Conc. A Export
  • SUN Yellow Extra Pure A
  • SUN Yellow A-FDC
  • Sunset Yellow FCF 6
  • Sunset Yellow FCF Supra
  • Sunset Yellow FU
  • Sunset Yellow FU Supra
  • Usacert FD&C Yellow No. 6
  • Yellow Orange S Specially Pure
  • Yellow Orange Specially Pure 85
  • Yellow SY for food
  • Gelborange-S
  • Zlut potravinarska 3
  • UNII-H77VEI93A8
  • Vitasyn Orange
  • 12707-27-6
  • 1342-61-6

Applications:

HPLC Method for Analysis of Brilliant Blue FCF Tartrazine, Sunset Yellow FCF and Allura Red in Monster Energy Drinks on Newcrom BH Column

July 14, 2020

Separation type: Liquid Chromatography Mixed-mode




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Brilliant Blue FCF, also known as Blue 1, is an compound classified as a triarylmethane dye. Dry, it has the appearance of a light-blue powder, but when dissolved in water, turns deeper blue. Allura Red AC, also known as FD&C Red No. 40, is a red azo dye that is the most commonly used red dye in the United States. It is used anywhere from tattoos to children’s’ medications to drinks and food. If used in food it also has the E number E129. Allura red is sold as a dark red sodium salt, but when dissolved in water, the solution appears orange-red.Sunset Yellow FCF, also known as Orange Yellow S, C.I. 15985, or Yellow 6, is a petroleum-derived orange azo dye. When in powder form, it is Reddish-orange, but when dissolved in water, the liquid becomes bright yellow.The dye is banned or restricted in Norway, Finland and Sweden.
Tartrazine is a yellow food coloring agent. It’s a trisodium salt, and like many multi-charged molecules tends to exhibit significant tailing using reverse-phase HPLC columns. By using a mixed-mode column, specifically designed in mind for multiple charges, Newcrom BH can retain and separate dyes with perfect peak shape using a mobile phase of methanol (MeOH) and water with sulfuric acid (H2SO4) to facilitate ion-exchange. UV detection at 400nm.



High Performance Liquid Chromatography (HPLC) Method for Analysis of Brilliant Blue FCF, Tartrazine, Sunset Yellow FCF and Allura Red




 

Condition

Column Newcom BH, 4.6×50 mm, 5 µm, 100A
Mobile Phase MeOH/H2O – 75/25%
Buffer H2SO4 – 0.75%
Flow Rate 1.0 ml/min
Detection UV 400 nm

Description

Class of Compounds Acid, Dyes
Analyzing Compounds Brilliant Blue FCF, Allura Red, Tartrazine, Sunset Yellow FCF

 

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Allura Red (Red #40)
Brilliant Blue FCF (Blue 1)
Sunset Yellow (Yellow 6)
Tartrazine (FD&C Yellow 5)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Determination of Sunset yellow on Newcrom BH Column

July 2, 2020


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Sunset yellow (yellow 6) is a dye used in food, cosmetics and drugs. In the US, it has an acceptable daily intake of 3.75mg/kg. It can be retained on HPLC mixed-mode Newcrom BH column with a mobile phase of methanol (MeOH) and water with sulfuric acid (H2SO4) buffer. Vis detection at 480nm

Condition

Column Newcom BH, 4.6×50 mm, 5 µm, 100A
Mobile Phase MeOH/H2O – 75/25%
Buffer H2SO4 – 0.5%
Flow Rate 1.0 ml/min
Detection Vis 480 nm

Description

Class of Compounds Acid, Dyes
Analyzing Compounds Sunset yellow

 

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Sunset Yellow (Yellow 6)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Allura Red, Sunset Yellow, Tartrazine in Mountain Dew Live Wire at 2 Wavelengths

March 29, 2017

Sunset Yellow FCF, also known as Orange Yellow S, C.I. 15985, or Yellow 6, is a petroleum-derived orange azo dye. When in powder form, it is Reddish-orange, but when dissolved in water, the liquid becomes bright yellow. The dye is banned or restricted in Norway, Finland and Sweden. Obelisc N is a column with very polar characteristics. It contains embedded acidic and basic ionizable groups and can retain Sunset Yellow. The method is LC/MS and UV compatible and can be used as a general approach for analyzing similar compounds.

 

Condition

Column Obelisc N, 3.2×50 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 50/50%
Buffer AmFm pH 3.0 – 70 mM
Flow Rate 0.6 ml/min
Detection UV, 430, 525 nm

 

Description

Class of Compounds
Dye, Acid, Hydrophilic, Ionizable, Zwitterionic
Analyzing Compounds Allura Red, Sunset Yellow, Tartrazine

Application Column

Obelisc N

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options
Application Analytes:
Allura Red (Red #40)
HPLC Method for Analysis of Allura Red in Children’s Mucinex Multi-Syptom Cold
HPLC Method for Analysis of Allura Red in Robitussin Cough & Cold
HPLC Method for Analysis of Allura Red in Soft Drinks 2
HPLC Method for Analysis of Allura Red in Soft Drinks 3
HPLC Method for Analysis of Allura Red in Soft Drinks 4
HPLC Method for Analysis of Allura Red in Soft Drinks 5
HPLC Method for Analysis of Allura Red, Sunset Yellow, Tartrazine in Mountain Dew Live Wire at 1 Wavelength
HPLC Method for Analysis of Brilliant Blue and Allura Red in Children’s Mucinex Night Time Multi-Symptom Cold
Sunset Yellow (Yellow 6)
Tartrazine (FD&C Yellow 5)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Sunset Yellow in Walgreen’s Daytime Non-Drowsy Cold & Flu

March 29, 2017

Sunset Yellow FCF, also known as Orange Yellow S, C.I. 15985, or Yellow 6, is a petroleum-derived orange azo dye. When in powder form, it is Reddish-orange, but when dissolved in water, the liquid becomes bright yellow.The dye is banned or restricted in Norway, Finland and Sweden. Obelisc N is a column with very polar characteristics. It contains embedded acidic and basic ionizable groups and can retain Sunset Yellow. The method is LC/MS and UV compatible and can be used as a general approach for analyzing similar compounds.

 

Condition

Column Obelisc N, 3.2×50 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 50/50%
Buffer AmFm pH 3.0 – 70 mM
Flow Rate 0.6 ml/min
Detection UV, 525 nm

 

Description

Class of Compounds
Dye, Acid, Hydrophilic, Ionizable, Zwitterionic
Analyzing Compounds Sunset Yellow

 

Application Column

Obelisc N

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options
Application Analytes:
Sunset Yellow (Yellow 6)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.