Ibotenic acid

Ibotenic acid

CAS Number2552-55-8
Molecular FormulaC5H6N2O4
Molecular Weight158.11
InChI KeyIRJCBFDCFXCWGO-UHFFFAOYSA-N
LogP-3.9
Synonyms
  • Ibotenic acid
  • 2552-55-8
  • Ibotenate
  • (+/-)-Ibotenic acid
  • DL-Ibotenic acid
  • Ibotenic acid
  • 2552-55-8
  • Ibotenate
  • (+/-)-Ibotenic acid
  • DL-Ibotenic acid
  • (RS)-Ibotenic acid
  • 2-amino-2-(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid
  • alpha-Amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid
  • NSC204850
  • 2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid
  • 44AS82FRSI
  • CHEBI:5854
  • CHEMBL284895
  • (RS)-Ibotenic acid;DL-Ibotenic acid
  • NSC-204850
  • alpha-Amino-3-hydroxy-5-isoxazoleacetic acid
  • SR-01000075462
  • MFCD00069294
  • UNII-44AS82FRSI
  • NSC 204850
  • 5-Isoxazoleacetic acid, alpha-amino-2,3-dihydro-3-oxo-
  • (y)-Ibotenic acid
  • IBOTENICACID
  • (?)-Ibotenic acid
  • alpha-amino-3-hydroxy-5-isooxazolacetic acid
  • IBOTENIC ACID [MI]
  • 4-Isoxazoline-5-acetic acid, alpha-amino-3-oxo-
  • Lopac0_000651
  • MLS002153141
  • SCHEMBL153359
  • 4-Isoxazoline-5-acetic acid, .alpha.-amino-3-oxo-
  • Ibotenic acid, ~95%, solid
  • GTPL1371

Applications:

HPLC Method for Analysis of Ibotenic Acid on Primesep A Column

February 28, 2023

HPLC Method for Analysis of Ibotenic acid on Primesep A by SIELC Technologies

Separation type: Liquid Chromatography Mixed-mode

HPLC Method for Analysis of Ibotenic Acid on Primesep A by SIELC Technologies.
HPLC Method for Analysis of Ibotenic acid on Primesep A by SIELC Technologies

Ibotenic acid is a physchoactive NDMA and metabotropic glutamate receptor agonist with neurotoxic properties. These structurally similar psychoactive drugs can be retained, separated, and analyzed on a mixed-mode Primesep A column with a mobile phase consisting of water, Acetonitrile (MeCN), and Phosphoric acid (H3PO4). This analytical method can be UV detected at 210 nm with high resolution and peak symmetry.

High Performance Liquid Chromatography (HPLC) Method for Analysis of  Ibotenic Acid

Condition

ColumnPrimesep A, 4.6 x 150 mm, 5 µm, 100 A
Mobile PhaseMeCN/H2O – 5/95%
BufferH3PO4 – 0.1%
Flow Rate1.0 ml/min
DetectionUV 210 nm
Peak Retention Time4.12 min

Description

Class of CompoundsAcid
Analyzing CompoundsIbotenic acid

Application Column

Primesep A

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
Ibotenic acid

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Separation of Ibotenic Acid and Glutamic Acid on Primesep A Column

February 28, 2023

HPLC Method for Separation of Ibotenic Acid and Glutamic Acid on Primesep A by SIELC Technologies

Separation type: Liquid Chromatography Mixed-mode

HPLC Method for Separation of Ibotenic Acid and Glutamic Acid on Primesep A by SIELC Technologies
Method for Separation of Ibotenic Acid and Glutamic Acid on Primesep A by SIELC Technologies

Ibotenic acid is a physchoactive NDMA and metabotropic glutamate receptor agonist with neurotoxic properties. These structurally similar psychoactive drugs can be retained, separated, and analyzed on a mixed-mode Primesep A column with a mobile phase consisting of water, Acetonitrile (MeCN), and Phosphoric acid (H3PO4). This analytical method can be UV detected at 210 nm with high resolution and peak symmetry.

High Performance Liquid Chromatography (HPLC) Method for Analysis of  Ibotenic Acid and Glutamic Acid

Condition

ColumnPrimesep A, 4.6 x 150 mm, 5 µm, 100 A
Mobile PhaseMeCN/H2O – 5/95%
BufferH3PO4 – 0.1%
Flow Rate1.0 ml/min
DetectionUV 210 nm
Peak Retention Time3.22 min, 10.52 min

Description

Class of CompoundsAcid
Analyzing CompoundsIbotenic Acid, Glutamic Acid

Application Column

Primesep A

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
D-Glutamic acid
GLU (L-Glutamic acid)
Glutamic Acid
Ibotenic acid
L-Glutamic acid hydrochloride
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Separation of Ibotenic Acid and Muscimol on a Primesep 100 Column

February 24, 2023

HPLC Method for Separation of Ibotenic Acid and Muscimol on Primesep 100 by SIELC Technologies

Separation type: Liquid Chromatography Mixed-mode

HPLC Method for Separation of Ibotenic Acid and Muscimolon Primesep 100 Column by SIELC Technologies
Method for Separation of Ibotenic Acid and Muscimol on Primesep 100 by SIELC Technologies

Ibotenic acid is a physchoactive NDMA and metabotropic glutamate receptor agonist with neurotoxic properties. Muscimol (also known as agarin or pantherine) is a psychoactive GABA-A agonist. Both are naturally occurring compounds found in Amanita muscaria and related species of mushrooms. These structurally similar psychoactive drugs can be retained, separated, and analyzed on a mixed-mode Primesep 100 column with a mobile phase consisting of water, Acetonitrile (MeCN), and Sulfuric acid (H2SO4). This analytical method can be UV detected at 200 nm with high resolution and peak symmetry.

High Performance Liquid Chromatography (HPLC) Method for Analysis of  Ibotenic Acid and Muscimol

Condition

ColumnPrimesep 100, 4.6 x 150 mm, 5 µm, 100 A
Mobile PhaseMeCN/H2O – 20/80%
BufferH2SO4 – 0.05%
Flow Rate1.0 ml/min
DetectionUV 200 nm
Peak Retention Time2.22 min, 8.52 min

Description

Class of CompoundsAcid
Analyzing CompoundsIbotenic Acid, Muscimol

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
Ibotenic acid
Muscimol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.