Parabens

Parabens

Synonyms

    Applications:

    HPLC Analysis of Paraben Preservatives on Newcrom AH Column

    October 29, 2020


    HPLC.cloud
    View on hplc.cloud

     

    Condition

    Column Newcrom AH, 3.2×100 mm, 5 µm, 100A
    Mobile Phase MeCN/H2O – 30/70%
    Buffer H2SO4 – 0.1%
    Flow Rate 0.5 ml/min
    Detection UV, 270 nm

     

    Description

    Class of Compounds
    Preservatives,  Hydrophobic
    Analyzing Compounds Methyl Paraben, Ethyl Paraben, Propyl Paraben

     

    Application Column

    Newcrom AH

    The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

    Select options
    Application Analytes:
    Ethylparaben
    Methylparaben
    Methylparaben sodium
    Parabens
    Propylparaben
    Propylparaben sodium
    SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

    HPLC Separation of Parabens and Benzoic Acid

    June 5, 2006


    HPLC.cloud
    View on hplc.cloud

    Condition 1

    Column Newcrom B, 3.2×100 mm, 3 µm, 100A
    Mobile Phase MeCN/H2O – 40/60%
    Buffer
    Flow Rate 0.5 ml/min
    Detection UV 275nm

     


    Parabens possess antibacterial and antifungal properties and are therefore widely used in pharmaceutical and cosmetic industries as preservatives in products. Parabens and benzoic acid can be baseline separated in a short time frame using Primesep B2 reverse-phase HPLC column with a simple mobile phase of water, acetonitrile (ACN, MeCN) and phosphoric acid of 0.1% as buffer. UV detection at 210nm.

    Condition 2

    Column Primesep B2, 4.6×150 mm, 5 µm, 100A
    Mobile Phase MeCN/H2O
    Buffer H3PO4
    Flow Rate 1.0 ml/min
    Detection UV, 210 nm

     

    Description

    Class of Compounds
    Acid, Hydrophilic, Preservative
    Analyzing Compounds Methyl paraben, Benzoic Acid, Propyl paraben

     

    Application Column

    Newcrom B

    The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

    Select options

    Primesep B2

    The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

    Select options
    Application Analytes:
    Benzoic Acid
    Methylparaben
    Parabens
    Propylparaben

    Application Detection:
    UV Detection
    SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.