| Molecular Formula | C9H6O6 |
|---|---|
| Molecular Weight | 210.14 |
| InChI Key | ARCGXLSVLAOJQL-UHFFFAOYSA-N |
| LogP | 0.3 |
| Synonyms |
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Applications:
UV-Vis Absorption Spectrum of Trimellitic Acid
December 12, 2025
If you are looking for optimized HPLC method to analyze Trimellitic Acid check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
HPLC Method for Analysis of Trimellitic Acid on Newcrom BH Column on Alltesta™
December 1, 2025
HPLC Method for Trimellitic Acid on Newcrom BH by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Trimellitic Acid
Trimellitic Acid is an isomer of benzenetricarboxylic acid with the chemical formula C9H6O6. It is primarily used as carboxylate ligand in the synthesis of a wide range of metal-organic frameworks (MOFs).
Trimellitic Acid can be retained and analyzed using the Newcrom BH stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with sulfuric acid as a buffer. Detection is performed using UV.
| Column | Newcrom BH, 4.6 x 150 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeCN – 10% |
| Buffer | Sulfuric Acid |
| Flow Rate | 1.0 mL/min |
| Detection | UV 275 nm |
| Class of Compounds | Acid |
| Analyzing Compounds | Trimellitic Acid |
Application Column
Newcrom BH
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
HPLC Method for Analysis of Mellitic Acid and Trimellitic Acid on Newcrom BH Column
March 6, 2024
HPLC Method for Analysis of Mellitic acid, Trimellitic Acid on Newcrom BH Column by SIELC Technologies
Separation type: Liquid Chromatography Reversed-phase

Mellitic Acid is an aromatic dicarboxylic acid with the chemical formula C12H6O12. It is a white crystalline solid and is derived from benzoic acid. Mellitic acid is named after mellite, a mineral in which it was first discovered. It is not commonly encountered in everyday use and does not have widespread applications.
Mellitic acid is mainly of interest in the fields of chemistry and mineralogy, and its practical applications are limited compared to other acids.
Trimellitic acid is a tricarboxylic acid with the chemical formula C9H6O6. It is also known as benzene-1,2,4-tricarboxylic acid. Trimellitic acid is used in various industrial applications, including the production of certain polymers and resins. It has three carboxylic acid functional groups, making it a useful building block in the synthesis of materials such as trimellitic anhydride (TMA), which is commonly employed in the manufacture of high-performance plastics. The unique structure and properties of trimellitic acid contribute to its role in specific chemical processes and the creation of specialized materials.
Mellitic acid and trimellitic acid can be retained, separated and analyzed on a reversed-phase Newcrom BH column with a mobile phase consisting of water, Acetonitrile (MeCN), and sulfuric acid. This analytical method can be detected with high resolution and peak symmetry at a wavelength of 220 nm using UV detection
High Performance Liquid Chromatography (HPLC) Method for Analyses of Mellitic acid, Trimellitic Acid on Newcrom BH Column by SIELC Technologies
Condition
| Column | Newcrom BH, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O |
| Buffer | H2SO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 220 nm |
| Injection volume: | 2 µL |
| Sample | 0.1 mg/ml |
| Sample Diluent | H2O – 100% |
Description
| Class of Compounds | Acid |
| Analyzing Compounds | Mellitic acid, Trimellitic Acid |
Application Column
Newcrom BH
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Trimellitic Acid
HPLC Method for Analysis of Trimellitic Anhydride and Trimellitic Acid on Newcrom B Column
July 29, 2022
HPLC Method for Trimellitic anhydride, Trimellitic Acid on Newcrom B by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Trimellitic anhydride, Trimellitic Acid.
Trimellitic anhydride is a trifunctional, highly reactive aromatic anhydride with the chemical formula C9H4O5. It is used as a curing agent for epoxy and other resins; in vinyl plasticizers, paints, coatings, dyes, pigments and a wide variety of other manufactured products. It is a common precursor to plasticizers for polyvinyl chloride (PVC). In acidic water, Trimellitic Anhydride will ‘open up’ back into Trimellitic Acid.
Trimellitic Acid is an isomer of benzenetricarboxylic acid with the chemical formula C9H6O6. It is primarily used as carboxylate ligand in the synthesis of a wide range of metal-organic frameworks (MOFs).
Trimellitic anhydride, Trimellitic Acid can be separated, retained, and analyzed on a mixed-mode Newcrom B column with a mobile phase consisting of water, Acetonitrile (MeCN), and Formic acid (FA). This analytical method can be UV detected at 250 nm or via negatively-charged Electrospray Ionization (ESI-) with high resolution and peak symmetry.
| Column | Newcrom B, 4.6 x 150 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O -50/50% |
| Buffer | Formic Acid- 1.0% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 250 nm, ESI |
| Class of Compounds | Acid, Hydrophilic |
| Analyzing Compounds | Trimellitic anhydride, Trimellitic Acid |
Application Column
Newcrom B
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
Trimellitic anhydride




