HPLC Method for Analysis of Trimellitic Anhydride and Trimellitic Acid on Newcrom B Column

Separation type: Liquid Chromatography Mixed-mode

HPLC Method for Analysis of Trimellitic Anhydride and Trimellitic Acid on Newcrom B Column_1471

 

High Performance Liquid Chromatography (HPLC) Method for Analysis of Trimellitic Anhydride and Trimellitic Acid

Trimellitic Anhydride is a common precursor to plasticizers for polyvinyl chloride (PVC); it’s acid form is Trimellitic Acid. In acidic water, Trimellitic Anhydride will ‘open up’ back into Trimellitic Acid. Trimellitic Anhydride and Trimellitic Acid can be separated, retained, and analyzed on a mixed-mode Newcrom B column with a mobile phase consisting of water, Acetonitrile (MeCN), and Formic acid (FA). This analytical method can be UV detected at 250 nm or via negatively-charged Electrospray Ionization (ESI-) with high resolution and peak symmetry.

Condition
Column Newcrom B, 4.6×150 mm,  100A
Mobile Phase MeCN/H2O -50/50%
Buffer Formic Acid- 1.0%
Flow Rate 1.0 ml/min
Detection UV 250 nm, ESI

Description
Class of Compounds Acid, Hydrophilic
Analyzing Compounds Trimellitic Anhydride and Trimellitic Acid

 

Application Column

Newcrom B

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Trimellitic Acid
Trimellitic anhydride
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.