HPLC Method for Analysis of Mellitic acid, Trimellitic Acid on Newcrom BH Column by SIELC Technologies
Separation type: Liquid Chromatography Reversed-phase
Mellitic Acid is an aromatic dicarboxylic acid with the chemical formula C12H6O12. It is a white crystalline solid and is derived from benzoic acid. Mellitic acid is named after mellite, a mineral in which it was first discovered. It is not commonly encountered in everyday use and does not have widespread applications.
Mellitic acid is mainly of interest in the fields of chemistry and mineralogy, and its practical applications are limited compared to other acids.
Trimellitic acid is a tricarboxylic acid with the chemical formula C9H6O6. It is also known as benzene-1,2,4-tricarboxylic acid. Trimellitic acid is used in various industrial applications, including the production of certain polymers and resins. It has three carboxylic acid functional groups, making it a useful building block in the synthesis of materials such as trimellitic anhydride (TMA), which is commonly employed in the manufacture of high-performance plastics. The unique structure and properties of trimellitic acid contribute to its role in specific chemical processes and the creation of specialized materials.
Mellitic acid and trimellitic acid can be retained, separated and analyzed on a reversed-phase Newcrom BH column with a mobile phase consisting of water, Acetonitrile (MeCN), and sulfuric acid. This analytical method can be detected with high resolution and peak symmetry at a wavelength of 220 nm using UV detection
High Performance Liquid Chromatography (HPLC) Method for Analyses of Mellitic acid, Trimellitic Acid on Newcrom BH Column by SIELC Technologies
Condition
Column | Newcrom BH, 4.6 x 150 mm, 5 µm, 100 A |
Mobile Phase | MeCN/H2O |
Buffer | H2SO4 – 0.1% |
Flow Rate | 1.0 ml/min |
Detection | UV 220 nm |
Injection volume: | 2 µL |
Sample | 0.1 mg/ml |
Sample Diluent | H2O – 100% |
Description
Class of Compounds | Acid |
Analyzing Compounds | Mellitic acid, Trimellitic Acid |
Application Column
Newcrom BH
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Trimellitic Acid