Pyrilamine maleate

Pyrilamine maleate structural formula

CAS Number59-33-6
Molecular FormulaC21H27N3O5
Molecular Weight401.464
InChI KeyJXYWFNAQESKDNC-BTJKTKAUSA-N
LogP2.82
Synonyms
  • Pyrilamine maleate
  • (2Z)-But-2-enedioic acid--N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine (1/1)
  • 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
  • 59-33-6
  • 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-,
  • 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-,
  • 2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]-pyridine maleate
  • 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine Bimaleate
  • Anisopyradamine
  • Antamine
  • Anthisan maleate
  • Antihist
  • Antisan
  • Diaminide maleate
  • Enrumay
  • Histalet Forte
  • Histalon
  • Histapyran
  • Histatex
  • Histavet P
  • maleate de mepyramine
  • maleato de mepiramina
  • MALEINSAEURE-(2-(N-(2-DIMETHYLAMINO-AETHYL)-N-(P-METHOXY-BENZYL)-AMINO)-PYRIDIN) - SALZ
  • Mepyramine hydrogen maleinate
  • mepyramine maleate
  • Mepyraminmaleat
  • Minihist
  • Neoantergan maleate
  • Neo-Antergan maleate
  • N-p-Methoxybenzyl-N',N'-dimethyl-N-?-pyridylethylenediamine maleate
  • NSC 3604
  • Paramal
  • Paraminyl
  • Paraminyl maleate
  • Prefrin A
  • Pymafed
  • Pyra Maleate
  • Pyramal
  • Pyranilamine maleate
  • Pyraninyl
  • Pyranisamine maleate
  • Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, maleate (1:1)
  • Renstamin
  • Stamine
  • Stangen
  • Stangen maleate
  • Statomin maleate
  • Thylogen
  • Thylogen maleate
  • 2786 R.P. maleate
  • N-Dimethylaminoethyl-N-p-methoxy-alpha-aminopyridine maleate
  • N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyridyl)ethylenediamine maleate
  • Dorantamin maleate
  • EINECS 200-422-7
  • Histine
  • Histosol
  • Kriptin maleate
  • N-p-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine maleate
  • Pyramal maleate
  • Pyra-Maleate
  • UNII-R35D29L3ZA
  • 5572-06-5

Applications:

HPLC Separation of Acetaminophen, Caffeine and Pyrilamine maleate

March 2, 2018

Acetaminophen is a p-aminophenol derivative with analgesic and antipyretic activities. It has weak anti-inflammatory properties, may cause liver, blood cell, and kidney damage. It is a nonprescription medication for mild-to-moderate pain and fever. Caffeine is a Central Nervous System (CNS) stimulant. It is an unregulated and legal drug in most parts of the world. It can be found in the seeds and leaves in a number of plants native in Africa, East Asia and South America. Pyrilamine maleate is a histamine H1 antagonist with hypnotic properties. It has multiple uses such as an anesthetic and is used against allergies. Newcrom R1, a column that takes advantage of the newest technologies, does not contain embedded acidic nor basic ionizable groups and can retain Acetaminophen, Caffeine and Pyrilamine maleate. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Acetaminophen (Paracetamol)
Caffeine
Maleate
Pyrilamine
Pyrilamine maleate
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Pyrilamine maleate on Newcrom R1 HPLC column

February 16, 2018
Separation of Pyrilamine maleate on Newcrom C18 HPLC column

Pyrilamine maleate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Pyrilamine maleate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.