| CAS Number | 126-83-0 |
|---|---|
| Molecular Formula | C3H6ClNaO4S |
| Molecular Weight | 196.581 |
| InChI Key | TZLNJNUWVOGZJU-UHFFFAOYSA-M |
| LogP | -2.32 |
| Synonyms |
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Applications:
HPLC Method for Analysis of Sodium 3-chloro-2-hydroxypropane-1-sulfonate on Newcrom BH
January 17, 2022
HPLC Method for Sodium 3-chloro-2-hydroxypropane-1-sulfonate on Newcrom BH by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Sodium 3-chloro-2-hydroxypropane-1-sulfonate.
Sodium 3-chloro-2-hydroxypropane-1-sulfonate is an anionic agent with the chemical formula C3H6ClNaO4S. It is used to prepare negatively charged probe particles to investigate the nanoporosity of cellulosic fibers and their interactions with cationic polyelectrolytes.
Sodium 3-chloro-2-hydroxypropane-1-sulfonate can be retained and analyzed using the Newcrom BH stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with an Ammonium Formate buffer. Detection is performed using ELSD
| Column | Newcrom BH, 3.2 x 100 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeOH/H2O – 10/90% |
| Buffer | Ammonium Formate pH 3.0 – 40 mM |
| Flow Rate | 0.5 ml/min |
| Detection | ELSD |
| Class of Compounds | Sulfonate |
| Analyzing Compounds | Sodium 3-chloro-2-hydroxypropane-1-sulfonate |
Application Column
Newcrom BH
Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
HPLC Method for Analysis of Sodium 3-chloro-2-hydroxypropane-1-sulfonate on Newcrom BH
January 17, 2022
HPLC Method for Sodium 3-chloro-2-hydroxypropane-1-sulfonate on Newcrom BH by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Sodium 3-chloro-2-hydroxypropane-1-sulfonate.
Sodium 3-chloro-2-hydroxypropane-1-sulfonate is an anionic agent with the chemical formula C3H6ClNaO4S. It is used to prepare negatively charged probe particles to investigate the nanoporosity of cellulosic fibers and their interactions with cationic polyelectrolytes.
Sodium 3-chloro-2-hydroxypropane-1-sulfonate can be retained and analyzed using the Newcrom BH stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a sulfuric acid buffer. Detection is performed using UV.
Condition
| Column | Newcrom BH, 3.2 x 100 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeOH/H2O – 10/90% |
| Buffer | H2SO4 – 0.2% |
| Flow Rate | 0.5 ml/min |
| Detection | UV 200 nm |
| Class of Compounds | Sulfonate |
| Analyzing Compounds | Sodium 3-chloro-2-hydroxypropane-1-sulfonate |
Application Column
Newcrom BH
Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
Separation of Sodium 3-chloro-2-hydroxypropane-1-sulfonate on Newcrom R1 HPLC column
February 16, 2018
Sodium 3-chloro-2-hydroxypropane-1-sulfonate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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