Lycopene

CAS Number502-65-8
Molecular FormulaC40H56
Molecular Weight536.9
InChI KeyOAIJSZIZWZSQBC-GYZMGTAESA-N
LogP15.6
Synonyms
  • LYCOPENE
  • 502-65-8
  • all-trans-Lycopene
  • Psi,psi-carotene
  • lycored
  • Redivivo
  • Mexoryl SAQ
  • Tomat-O-Red
  • (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
  • (all-e)-lycopene
  • Solanorubin
  • Ateronon
  • (all-trans)-lycopene
  • TOMATO LYCOPENE
  • Aec lycopene
  • Blakeslea trispora
  • DTXSID2046593
  • CI 75125
  • SB0N2N0WV6
  • INS-160D(III)
  • INS NO.160D(III)
  • Lycopene from blakeslea trispora
  • FEMA NO. 4110
  • E-160D(III)
  • NSC-407322
  • DTXCID0026593
  • CHEBI:15948
  • All trans Lycopene
  • NSC407322
  • 2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
  • Pro Lycopene
  • Pro-Lycopene
  • psi, psi-Carotene
  • LYCOMATO
  • LYC O MATO
  • DTXSID70859421
  • RefChem:5967
  • DTXCID60809733
  • 207-949-1
  • trans-Lycopene
  • Lycopene 7
  • y,y-Carotene
  • Lycopene, all-trans-
  • C40H56
  • MFCD00017350
  • NSC 407322
  • C.I. 75125
  • LYC-O-MATO
  • NCGC00166291-01
  • Lycopene (>80%)
  • .psi.,.psi.-Carotene
  • (all-E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene
  • Lycopene (VAN)
  • CCRIS 7925
  • EINECS 207-949-1
  • UNII-SB0N2N0WV6
  • psi-psi-carotene
  • Lyco Vit
  • ?,?-carotene
  • LYC
  • Lycopene preparation
  • Natural Yello 27
  • Lycopene all-trans-
  • |x,?|x-?carotene
  • Lycopene [M+H]+
  • LYCOPENE [MI]
  • LYCOPENE [VANDF]
  • LYCOPENE [MART.]
  • LYCOPENE [WHO-DD]
  • SCHEMBL20158
  • BSPBio_003389
  • Lycopene, analytical standard
  • E160d
  • TOMATO LYCOPENE [FHFI]
  • CHEMBL501174
  • Lycopene, >=90%, from tomato
  • MSK2456
  • WLZ4685
  • GLXC-06674
  • HY-N0287
  • Tox21_112395
  • EBC-27292
  • LMPR01070257
  • s3943
  • LYCOPENE PREPARATION [USP-RS]
  • AKOS015961276
  • CS-6378
  • DB11231
  • EBC-616775
  • FD10111
  • NCGC00166291-02
  • NCGC00166291-03
  • NCGC00166291-04
  • AC-13571
  • AC-33932
  • CAS-502-65-8
  • LS-15428
  • Lycopene, >=98% (HPLC), from tomato
  • SY104736
  • L0257
  • L9609
  • NS00013534
  • LYCOPENE FROM BLAKESLEA TRISPORA [FCC]
  • C05432
  • M01302
  • SBI-0654183.0001
  • Q208130
  • BRD-K37083340-001-02-3
  • Lycopene, United States Pharmacopeia (USP) Reference Standard
  • Lycopene, Pharmaceutical Secondary Standard; Certified Reference Material
  • (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene
  • 2,6,8,10,12,14,16,18,20,22,24,26,30-Dotriacontatridecaene, 2,6,10,14,19,23,27,31-octamethyl-, (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-
  • 2,6,8,10,12,14,16,18,20,22,24,26,30-Dotriacontatridecaene, 2,6,10,14,19,23,27,31-Octamethyl-, (all-E)-

Applications:

HPLC Method for Analysis of Lycopene on Lipak Column

July 9, 2026

HPLC Method for Analysis of Lycopene on Lipak Column by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Lycopene.

Lycopene is a carotenoid hydrocarbon with C40H56 molecular formula. It is found primarily in tomatoes, watermelon, grapefruits, and red guavas. Gac has the highest concentration of lycopene at 2~6 per gram. Lycopene in non-toxic, but can be a rare allergen. You can find detailed UV spectra of Lycopeneand information about its various lambda maxima by visiting the following link.

Lycopene can be retained and analyzed using the Lipak stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) and ethanol. Detection is performed using UV.

Condition

ColumnLipak, 3.2 x 150 mm, 5 µm, 100 A, dual ended
Mobile PhaseMeCN/EtOH – 40%
BufferNone
Flow Rate0.5 ml/min
DetectionVis 427 nm
Limit Of Detection*0.2 ppm
*LOD was determined for this combination of instrument, method, and analyte, and it can vary from one laboratory to another even when the same general type of analysis is being performed.

Description

Class of CompoundsHydrocarbon
Analyzing CompoundsLycopene

Application Column

Lipak

Column Diameter: 3.2 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Lycopene
Application Detection:
Vis Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Uv-Vis Spectrum of Lycopene

July 8, 2026

Access the UV-Vis Spectrum SIELC Library

If you are looking for optimized HPLC method to analyze Lycopene check our HPLC Applications library

UV/Vis.: λmax: 284, 295, 346, 362, 446, 472, 502 nm

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The compound was dissolved in ethanol. This analysis was done with the mobile phase of hexane, IPA, and TFA.

 

 

Application Analytes:
Lycopene
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.