5-Hydroxymethyl-2-furaldehyde (5-HMF)

CAS Number67-47-0
Molecular FormulaC6H6O3
Molecular Weight126.11
InChI KeyNOEGNKMFWQHSLB-UHFFFAOYSA-N
LogP-0.6
Synonyms
  • 5-HYDROXYMETHYLFURFURAL
  • 67-47-0
  • 5-(hydroxymethyl)furan-2-carbaldehyde
  • 5-Hydroxymethyl-2-furaldehyde
  • 5-(Hydroxymethyl)furfural
  • 5-(Hydroxymethyl)-2-furaldehyde
  • Hydroxymethylfurfural
  • 5-(Hydroxymethyl)-2-furfural
  • 5-Oxymethylfurfurole
  • 5-Hydroxymethylfuraldehyde
  • Hydroxymethylfurfurole
  • 5-Hydroxymethylfuran-2-aldehyde
  • Hydroxymethylfurfuraldehyde
  • Hydroxymethylfurfuralaldehyde
  • 2-Hydroxymethyl-5-furfural
  • 2-Furancarboxaldehyde, 5-(hydroxymethyl)-
  • 5-Hydroxymethyl-2-formylfuran
  • 5-(Hydroxymethyl)-2-furancarbonal
  • 5-(Hydroxymethyl)-2-furfuraldehyde
  • 5-Hydroxymethyl-2-furfural
  • 5-Hydroxymethylfurfuraldehyde
  • 5-hydroxymethyl furfural
  • 5-(Hyddroxymethyl)furfurole
  • 5-(Hydroxymethyl)-2-furancarboxaldehyde
  • 5-Hydroxymethyl-2-furancarboxaldehyde
  • 5-HYDROXYMETHYL-FURFURAL
  • HMF
  • 2-Furaldehyde, 5-(hydroxymethyl)-
  • NSC-40738
  • CHEBI:412516
  • 5-(Hydroxymethyl)furan-2-aldehyde
  • 5-Hydroxymethyl-2-furancarbaldehyde
  • Aes-103
  • 5-HMF

Applications:

Substituted Furans Separation on Newcrom R1

February 10, 2021

Furan is a chemical contaminant that forms in some foods during traditional heat treatment techniques, such as cooking, jarring, and canning.  The compounds can be retained and separated in HPLC using Newcrom R1 reverse-phase column.  The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 210 and 275 nm.

Condition

Column Newcrom R1, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 5/95%
Buffer H3PO4 – 0.1%
Flow Rate 1.0 ml/min
Detection 210, 275 nm

Description

Class of Compounds Hydrophilic, Acid, Aldehyde
Analyzing Compounds 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furaldehyde (5-HMF), 5-(Hydroxymethyl)furan-2-carboxylic Acid, Furfuryl Alcohol, Furfural, 2-furancarboxylic acid

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
2-Furancarboxylic acid
3,4-Bis(hydroxymethyl)furan
5-Hydroxymethyl-2-furaldehyde (5-HMF)
5-Hydroxymethyl-2-furancarboxylic acid
Furfural
Furfuryl alcohol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Determination of 5-Hydroxymethyl-2-furaldehyde (5-HMF) on Newcrom R1 Column by SIELC Technologies

January 29, 2021


HPLC.cloud
View on hplc.cloud

HPLC Determination of 5-Hydroxymethyl-2-furaldehyde (5-HMF) on Newcrom R1 Column by SIELC Technologies


5-Hydroxymethyl-2-furaldehyde (HMF), also known as 5-(Hydroxymethyl)furfural, is an organic compound derived from sugars and is of interest due to its potential as a platform chemical for biofuels and biochemicals.

HMF plays a notable role in the flavor and aroma development of whisky. Understanding its formation, impact, and concentration can provide insights into the aging process and overall quality of the whisky, contributing to the appreciation and enjoyment of this complex beverage.

Furan is a chemical contaminant that forms in some foods during traditional heat treatment techniques, such as cooking, jarring, and canning. The compounds can be retained and separated in HPLC using Newcrom R1 reverse-phase column. The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 210 and 275 nm.

ColumnNewcrom R1, 4.6×150 mm, 5 µm, 100A
Mobile PhaseMeCN/H2O – 5/95%
BufferH3PO4 – 0.1%
Flow Rate1.0 ml/min
Detection284 nm
Class of CompoundsHydrophilic
Analyzing Compounds5-Hydroxymethyl-2-furaldehyde (5-HMF)

Application Column

Newcrom R1

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
5-Hydroxymethyl-2-furaldehyde (5-HMF)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.