2-Furancarboxylic acid

2-Furancarboxylic acid structural formula

CAS Number88-14-2
Molecular FormulaC5H4O3
Molecular Weight112.084
InChI KeySMNDYUVBFMFKNZ-UHFFFAOYSA-N
LogP0.64
Synonyms
  • 2-Furancarboxylic acid
  • Furan-2-carboxylic acid
  • 88-14-2
  • 2-Furoic acid
  • 5-18-06-00102
  • 2-Carboxyfuran
  • 2-Furanoic acid
  • Acide 2-furoique
  • acido 2-furoico
  • BRENZSCHLEIMSAEURE
  • Furan-2-carbonsaure
  • FURAN-2-CARBOXYLIC ACID
  • NSC 58965
  • NSC 8842
  • Pyromucic acid
  • ?-Furancarboxylic acid
  • ?-Furoic acid
  • BRN 0110149
  • EINECS 201-803-0
  • Kyselina 2-furoova
  • Kyselina pyroslizova
  • UNII-P577F6494A
  • 2-Furanoate
  • 2-Furoate
  • Furan-2-carbonsaeure
  • Furancarboxylate
  • Furancarboxylic acid
  • Furoate
  • Furoic acid
  • Pyromucate
  • a-Furancarboxylate
  • a-Furancarboxylic acid
  • a-Furoate
  • a-Furoic acid
  • alpha-Furancarboxylate
  • alpha-Furoate
  • alpha-furancarboxylic acid
  • alpha-furoic acid
  • b-Furancarboxylate
  • b-Furancarboxylic acid
  • b-Furoate
  • b-Furoic acid
  • beta-Furancarboxylate
  • beta-Furancarboxylic acid
  • beta-Furoate
  • beta-Furoic acid

Applications:

Substituted Furans Separation on Newcrom R1

February 10, 2021

Furan is a chemical contaminant that forms in some foods during traditional heat treatment techniques, such as cooking, jarring, and canning.  The compounds can be retained and separated in HPLC using Newcrom R1 reverse-phase column.  The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 210 and 275 nm.

Condition

Column Newcrom R1, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 5/95%
Buffer H3PO4 – 0.1%
Flow Rate 1.0 ml/min
Detection 210, 275 nm

Description

Class of Compounds Hydrophilic, Acid, Aldehyde
Analyzing Compounds 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furaldehyde (5-HMF), 5-(Hydroxymethyl)furan-2-carboxylic Acid, Furfuryl Alcohol, Furfural, 2-furancarboxylic acid

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
2-Furancarboxylic acid
3,4-Bis(hydroxymethyl)furan
5-Hydroxymethyl-2-furaldehyde (5-HMF)
5-Hydroxymethyl-2-furancarboxylic acid
Furfural
Furfuryl alcohol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of 2-Furancarboxylic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of 2-Furancarboxylic acid on Newcrom C18 HPLC column

2-Furancarboxylic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
2-Furancarboxylic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.