Thiamphenicol

Thiamphenicol structural formula

CAS Number15318-45-3
Molecular FormulaC12H15Cl2NO5S
Molecular Weight356.210
InChI KeyOTVAEFIXJLOWRX-NXEZZACHSA-N
LogP-0.270
Synonyms
  • Thiamphenicol
  • 2,2-Dichloro-N-{(1R,2R)-1,3-dihydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide
  • Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-
  • 15318-45-3
  • Descocin
  • Dexawin
  • Dextrosulphenidol
  • Efnicol
  • EINECS 239-355-3
  • Hyrazin
  • Igralin
  • Macphenicol
  • Masatirin
  • Methylsulfonylchloramphenicol
  • Neomyson
  • NSC 522822
  • Rincrol
  • Thiamcol
  • Thiocymetin
  • Thiophenicol
  • Unaseran-D
  • Urfamicina
  • Urfamycine
  • Urophenyl
  • (+)-Thiamphenicol
  • D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
  • D-Thiocymetin
  • D-Thiophenicol
  • D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
  • Thiamphenicolum
  • Tiamfenicol
  • Tiamfenicolo
  • UNII-FLQ7571NPM
  • Armai (TN)
  • D-(+)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide
  • Thiocymetin (TN)

Applications:

Separation of Thiamphenicol on Newcrom R1 HPLC column

February 16, 2018
Separation of Thiamphenicol on Newcrom C18 HPLC column

Thiamphenicol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Thiamphenicol
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.

HPLC Method for Analysis of Pesticides: Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin on Primesep B2 Column

July 11, 2017

 

Condition 
Column Primesep B2, 3.2×100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 – 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm

 

Description
Class of Compounds
 Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin

 

Application Column

Primesep B2

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Alachlor
Aniline
Diazinon
Simazine
Thiabendazole
Thiamphenicol
Trifluralin
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Pesticides: Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin on Primesep 100 Column

June 11, 2014

Condition 
Column Primesep 100, 3.2×100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 – 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm

 

Description
Class of Compounds
 Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin

 

Application Column

Primesep 100

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
(2H7)Aniline
Alachlor
Diazinon
Simazine
Thiabendazole
Thiamphenicol
Trifluralin
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.