Simazine

Simazine structural formula

CAS Number122-34-9
Molecular FormulaC7H12ClN5
Molecular Weight201.661
InChI KeyODCWYMIRDDJXKW-UHFFFAOYSA-N
LogP2.18
Synonyms
  • Simazine
  • 6-Chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine
  • 1,3,5-Triazine-2,4-diamine, 6-chloro-N2,N4-diethyl-
  • 122-34-9
  • 1,3,5-Triazine-2,4-diamine, 6-chloro-N,N'-diethyl-
  • Princep
  • 1,3,5-Triazine-2,4-diamine, 6-chloro-N2,N4-diethyl-
  • 2,4-Bis(ethylamino)-6-chloro-s-triazine
  • 2,4-Di(ethylamino)-6-chloro-1,3,5-triazine
  • 2-Chloro-4,6-bis(ethylamino)-1,3,5-triazine
  • 2-Chloro-4,6-bis(ethylamino)-s-triazine
  • 2-Chloro-4,6-bis(ethylamino)-sym-triazine
  • 4,6-Bis(ethylamino)-2-chlorotriazine
  • 6-Chloro-N,N'-diethyl-1,3,5-triazine-2,4-diamine
  • Aktinit S
  • Aquazine
  • Batazina FLO
  • Bitemol S 50
  • Geigy 27692
  • Gesatop
  • Gesatop D
  • Herbatoxol S
  • Herbazin
  • Herbazin 50
  • Herboxy
  • Hungazin DT
  • NSC 25999
  • Premazine
  • Radocon
  • Radokor
  • Simanex
  • Simatox
  • Simatsin-neste
  • Simazin
  • Simazin S 50
  • simazina
  • Simazine 50
  • Simazine 80W
  • s-Triazine, 2-chloro-4,6-bis(ethylamino)-
  • Symazine
  • Tafazine
  • Tafazine 50W
  • Taphazine
  • Triazine A 384
  • Yrodazin
  • Amizine
  • Batazina
  • Batazine FLO
  • Bitemol
  • BRN 0010895
  • Caswell No. 740
  • Cekusan
  • Cekusima
  • Cekuzina-S
  • 1-Chloro-3,5-bis(ethylamino)-2,4,6-triazine
  • 6-Chloro-N2,N4-diethyl-1,3,5-triazine-2,4-diamine
  • EINECS 204-535-2
  • EPA Pesticide Chemical Code 080807
  • Geigy 27,692
  • Gesapun
  • Primatel S
  • Primatol S
  • Printop
  • Simadex
  • Tafazine 50-W
  • 2,4-Bis(aethylamino)-6-chlor-1,3,5-triazin
  • Herbazin-50
  • UNII-SG0C34SMY3
  • 2,4-bis(ethylamino)-6-chloro-1,3,5-triazine
  • 6-chloro-N(2),N(4)-diethyl-1,3,5-triazine-2,4-diamine
  • 6-chloro-N,N'-diethyl-[1,3,5]triazin-2,4-diamine
  • 11141-20-1
  • 119603-94-0
  • 12764-71-5
  • 39291-64-0

Applications:

HPLC Method for Analysis of Simazine on Primesep 100 Column

August 12, 2024

High Performance Liquid Chromatography (HPLC) Method for Analysis of Simazine on Primesep 100 by SIELC Technologies

Separation type: Liquid Chromatography Mixed-mode SIELC Technologies

HPLC Method for Analysis of Simazine on Primesep 100 Column


 High Performance Liquid Chromatography (HPLC) Method for Analysis of Simazine

Simazine is a herbicide that belongs to the class of triazine herbicides. It is commonly used for controlling broadleaf weeds and grasses in agricultural and non-agricultural settings.

Simazine can be retained, separated and analyzed using a Primesep 100 mixed-mode stationary phase column. The analysis employs a gradient method with a simple mobile phase comprising water, acetonitrile (MeCN), and sulfuric acid as a buffer. This method allows for detection using UV 250 nm.

You can find detailed UV spectra of Simazine and information about its various lambda maxima by visiting the following link.

ColumnPrimesep 100, 4.6 x 50 mm, 5 µm, 100 A
Mobile PhaseMeCN – 50%
BufferH2SO4 – 0.1%
Flow Rate1.0 ml/min
DetectionUV 250 nm
Limit of Detection30 ppb
* LOD was determined for this combination of instrument, method, and analyte, and it can vary from one laboratory to another even when the same general type of analysis is being performed.

Class of Compounds
Herbicide
Analyzing CompoundsSimazine

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 50 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
Simazine
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of Pesticides, Herbicides, Fungicides and Insecticides on Newcrom BH Column

May 22, 2020


Herbicides are used to control unwanted plants, they are also known as weedkillers. Insecticides are used to kill insects. Fungicides are used to kill parasitic fungi. Pesticide is a more generic term that includes herbicides, fungicides and insecticides in its definition. All are heavily used in agriculture. By using HPLC, many different pesticides can be separated and their retention characteristics controlled using the Newcrom BH mixed-mode column. It can be used with different organic media such as acetonitrile (ACN) or methanol (MeOH). By varying the concentration of organic modifier and using different buffers like sulfuric acid (H2SO4), ammonium formate (AmFm), or formic acid, separation of desired pesticides can be achieved.

Condition
Column Newcrom BH, 3.2×100 mm, 5 µm, 100A
Mobile Phase MeCN, MeOH
Buffer H2SO4, Formic acid, AmFm pH 3.0
Flow Rate 0.6 ml/min
Detection UV 275 nm

Description
Class of Compounds Pesticides, Herbicides, Fungicides, Insecticides
Analyzing Compounds Monocrotophos, Metribuzin, Bromacil, Carbofuran, 4-Chlorophenoxyacetic acid, Bentazone, Folpet, Fenthion, Fenvalerate, Metrabuzin, Carbofuran, Atrazine, Parathion –methyl, MCPA, Clopyralid, Dicamba, Benthazon, Simazine, Diuron, MCPB, Mecoprop, 4-Chlorophenoxyacetic acid,2,4,5-T

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
2,4,5-Trichlorophenoxyacetic acid
4-CPA
Atrazine
Bentazone-sodium
Carbofuran
Clopyralid
Dicamba
Diuron
Fenvalerate
Folpet
MCPA
MCPB
Mecoprop
Methyl parathion
Metribuzin
Monocrotophos
Simazine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Simazine on Newcrom R1 HPLC column

February 16, 2018
Separation of Simazine on Newcrom C18 HPLC column

Simazine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Simazine
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.

HPLC Method for Analysis of Pesticides: Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin on Primesep B2 Column

July 11, 2017

 

Condition 
Column Primesep B2, 3.2×100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 – 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm

 

Description
Class of Compounds
 Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin

 

Application Column

Primesep B2

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Alachlor
Aniline
Diazinon
Simazine
Thiabendazole
Thiamphenicol
Trifluralin
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Pesticides: Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin on Primesep 100 Column

June 11, 2014

Condition 
Column Primesep 100, 3.2×100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 – 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm

 

Description
Class of Compounds
 Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin

 

Application Column

Primesep 100

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A

Add to cart
Application Analytes:
(2H7)Aniline
Alachlor
Diazinon
Simazine
Thiabendazole
Thiamphenicol
Trifluralin
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.