Tetraxetan (DOTA)

CAS Number60239-18-1
Molecular FormulaC16H28N4O8
Molecular Weight404.42
InChI KeyWDLRUFUQRNWCPK-UHFFFAOYSA-N
LogP-10.6
Synonyms
  • DOTA
  • Tetraxetan
  • 60239-18-1
  • 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid
  • Dota acid
  • 1,4,7,10-Dota
  • UNII-1HTE449DGZ
  • 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid
  • CHEBI:61028
  • 1HTE449DGZ
  • MLS001333612
  • 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
  • NSC681107
  • 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid
  • 2,2',2',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetryl)tetraacetic acid
  • AK124371
  • SMR000857276
  • J-650232
  • 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraaceticacid
  • Eu-Tetraxetan

Applications:

HPLC Separation of DOTA and DO3A MS- compatible mobile phase

September 25, 2019

 

Condition
Column Primesep 100, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer AmFm pH 3.0- 30 mM
Flow Rate  1.0 ml/min
Detection CAD (Corona) MS- compatible mobile phase


Description
Class of Compounds
 Acid, Hydrophilic, Ionizable, Carboxylic acid, Carbocyclic.
Analyzing Compounds 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA), DO3A

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
DO3A
Tetraxetan (DOTA)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of DOTA and DO3A on Primesep 100 Column

September 25, 2019

Condition
Column Primesep 100, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 50/50%
Buffer H2SO4 – 0.1 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description
Class of Compounds
 Acid, Hydrophilic, Ionizable, Carboxylic acid, Carbocyclic.
Analyzing Compounds 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA), DO3A

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
DO3A
Tetraxetan (DOTA)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.