Meglumine (N-Methyl-D-glucamine)

CAS Number6284-40-8
Molecular FormulaC7H17NO5
Molecular Weight195.21
InChI KeyMBBZMMPHUWSWHV-BDVNFPICSA-N
LogP-2.8
Synonyms
  • meglumine
  • N-Methyl-D-glucamine
  • 6284-40-8
  • N-Methylglucamine
  • Meglumin
  • 1-Deoxy-1-(methylamino)-D-glucitol
  • Methylglucamin
  • Meglumina
  • Megluminum
  • 1-Deoxy-1-methylaminosorbitol
  • N-Methylsorbitylamine
  • D-Glucitol, 1-deoxy-1-(methylamino)-
  • (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
  • (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol
  • N-Methyl-D(-)-glucamine
  • Megluminum [INN-Latin]
  • UNII-6HG8UB2MUY
  • Meglumina [INN-Spanish]
  • Sorbitol, 1-deoxy-1-methylamino-
  • 6HG8UB2MUY
  • CHEBI:59732
  • NSC 7391
  • NSC 52907
  • DSSTox_CID_3244
  • DSSTox_RID_76939
  • DSSTox_GSID_23244
  • Glucitol, 1-deoxy-1-(methylamino)-, D-
  • C7H17NO5
  • EINECS 228-506-9
  • N-Methylglucamine solution
  • NSC-7391
  • NSC52907
  • NSC-52907
  • Meglumine [USP:INN:BAN:JAN]
  • N-methyl-glucamine
  • N-Methyl glucamine
  • NCGC00166125-01
  • CAS-6284-40-8
  • MFCD00004707
  • d(-)-n-methylglucamine
  • N-Methylglucamine solution (70% or less)
  • EC 228-506-9
  • SCHEMBL2193

Applications:

HPLC Method for Determination of Flunixin and Meglumine on Primesep 100 Column

September 27, 2022

HPLC Method for Meglumine (N-Methyl-D-glucamine), Flunixin on Primesep 100 by SIELC Technologies

HPLC Method for Determination of Flunixin Meglumine on Primesep 100 Column by SIELC Technologies
HPLC Method for Determination of Meglumine (N-Methyl-D-glucamine), Flunixin on Primesep 100 by SIELC Technologies

Flunixin is an analgesic and antipyretic nonsteroidal anti-inflammatory drug (NSAID) with the chemical formula C14H11F3N2O2. It is used primarily by veterinarians in bovine and equine treatments. Prolonged consecutive use can cause health problems due to toxicity. Due to that, it is a prohibited substance under International Federation for Equestrian Sports rules. It is typically produced as a Meglumine salt, which helps stabilize and bulk up the medication in its solid form. You can find detailed UV spectra of Flunixin and information about its various lambda maxima by visiting the following link.

Meglumine is a sugar alcohol with the chemical formula C7H17NO5. It is a derivative of glucose that is used primarily as an excipient in pharmaceuticals. You can find detailed UV spectra of Meglumine and information about its various lambda maxima by visiting the following link.

Meglumine (N-Methyl-D-glucamine), Flunixin can be retained, separated, and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple isocratic mobile phase of water, Acetonitrile (MeCN), and a sulfuric acid (H2SO4) buffer.  This analysis method can be UV detected at 252 nm (Flunixin) with high resolution and peak symmetry and is compatible with Mass Spectrometry (MS), ELSD, and CAD.

Condition

Column Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN – 60%
Buffer TFA – 0.2%
Flow Rate 1.0 ml/min
Detection ELSD, 50C, UV 252 nm

 

Description

Class of Compounds Drug
Analyzing Compounds Meglumine (N-Methyl-D-glucamine), Flunixin

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Flunixin
Meglumine (N-Methyl-D-glucamine)

Application Detection:
UV Detection
ELSD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Meglumine on Primesep 100 Column by SIELC Technologies

September 26, 2022

HPLC Method for Meglumine (N-Methyl-D-glucamine) on Primesep 100 by SIELC Technologies

HPLC Method for Analysis of Meglumine on Primesep 100 Column by SIELC Technologies
HPLC Method for Analysisof Meglumine on Primesep 100 Column by SIELC Technologies

Meglumine is a sugar alcohol with the chemical formula C7H17NO5. It is a derivative of glucose that is used primarily as an excipient in pharmaceuticals. You can find detailed UV spectra of Meglumine and information about its various lambda maxima by visiting the following link.

Meglumine (N-Methyl-D-glucamine) can be retained and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple isocratic mobile phase of water, Acetonitrile (MeCN), and a sulfuric acid (H2SO4) buffer. This analysis method can be detected and is compatible with Mass Spectrometry (MS), ELSD, and CAD. 

Condition

ColumnPrimesep 100, 2.1 x 100 mm, 3 µm, 100 A, dual ended
Mobile PhaseMeCN – 10%
BufferTFA – 0.2%
Flow Rate0.2 ml/min
DetectionELSD, 50C
Retention Time3.2 min

Description

Class of Compounds Drug
Analyzing CompoundsMeglumine (N-Methyl-D-glucamine)

Application Column

Primesep 100

Column Diameter: 2.1 mm
Column Length: 100 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Meglumine (N-Methyl-D-glucamine)

Application Detection:
ELSD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.