HPLC Method for Meglumine (N-Methyl-D-glucamine) on Primesep 100 by SIELC Technologies
Meglumine is a sugar alcohol with the chemical formula C7H17NO5. It is a derivative of glucose that is used primarily as an excipient in pharmaceuticals. You can find detailed UV spectra of Meglumine and information about its various lambda maxima by visiting the following link.
Meglumine (N-Methyl-D-glucamine) can be retained and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple isocratic mobile phase of water, Acetonitrile (MeCN), and a sulfuric acid (H2SO4) buffer. This analysis method can be detected and is compatible with Mass Spectrometry (MS), ELSD, and CAD.
Condition
| Column | Primesep 100, 2.1 x 100 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeCN – 10% |
| Buffer | TFA – 0.2% |
| Flow Rate | 0.2 ml/min |
| Detection | ELSD, 50C |
| Retention Time | 3.2 min |
Description
| Class of Compounds | Drug |
| Analyzing Compounds | Meglumine (N-Methyl-D-glucamine) |
Application Column
Primesep 100
Column Diameter: 2.1 mm
Column Length: 100 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
Application Analytes:
Meglumine (N-Methyl-D-glucamine)Application Detection:
ELSD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.
