Separation type: Liquid Chromatography Mixed-mode
Meglumine is a sugar alcohol that is a common pharmaceutical excipient used to stabilize and bulk up the partner medication in its solid form. Meglumine can be retained and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple isocratic mobile phase of water, Acetonitrile (MeCN), and a sulfuric acid (H2SO4) buffer. This analysis method can be detected and is compatible with Mass Spectrometry (MS), ELSD, and CAD.
| Column | Primesep 100, 2.1×100 mm, 3 µm, 100A |
| Mobile Phase | MeCN – 10% |
| Buffer | TFA – 0.2% |
| Flow Rate | 0.2 ml/min |
| Detection | ELSD, 50C |
| Retention Time | 3.2 min |
| Class of Compounds | Drug |
| Analyzing Compounds | Meglumine |
Application Column
Primesep 100
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
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