| CAS Number | 638-23-3 |
|---|---|
| Molecular Formula | C5H9NO4S |
| Molecular Weight | 179.2 |
| InChI Key | GBFLZEXEOZUWRN-VKHMYHEASA-N |
| LogP | -3.1 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of Carbocisteine
January 9, 2026
If you are looking for optimized HPLC method to analyze Carbocisteine check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
HPLC Separation of Mixture of Carbocisteine, Methylparaben & Propylparaben on Primesep 100 Column
July 31, 2019
HPLC Method for Carbocisteine, Methylparaben sodium, Propylparaben sodium, Propylparaben, Methylparaben on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Carbocisteine, Methylparaben sodium, Propylparaben sodium, Propylparaben, Methylparaben.
Carbocysteine is a medication that reduces the viscosity of mucus making it easier to cough up. Methylparaben and propylparaben are used as preservatives in cosmetics, pharmaceuticals and food. They can be separated in HPLC on a Primesep 100 mixed-mode column by both hydrophobic and ionic properties present on the stationary phase. The analytical method uses acetonitrile (ACN) gradient and water with sulfuric acid (H2SO4) as buffer and UV detected at 200nm.
| Column | Primesep 100 |
| Mobile Phase | Gradient MeCN – 2-50%, 20 min |
| Buffer | H2SO4 – 0.05 % |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 200 nm |
| Class of Compounds |
Drug, Acid, Hydrophilic, Ionizable, Carboxylic acid, Carbocyclic, Benzoate, Hydroxy Acid, Amino Acid, Hydroxybenzoate, Phenol |
| Analyzing Compounds | Carbocisteine, Methylparaben sodium, Propylparaben sodium, Propylparaben, Methylparaben |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Methylparaben
Methylparaben sodium
Propylparaben
Propylparaben sodium
HPLC Determination of Carbocisteine on Primesep 100 Column
July 31, 2019
HPLC Method for Carbocisteine, S-(Carboxymethyl)-L-cysteine on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Carbocisteine, S-(Carboxymethyl)-L-cysteine.
Carbocisteine, or carbocysteine, is a drug designed to clear the mucus from the upper and lower airways. It’s primarily available in tablet form. It can be retained on a Primesep 100 Column in about 5 minutes. Primesep 100 is a reverse-phase (RP) mixed-mode column with embedded acidic ion-pairing groups.
Condition
Column Primesep 100 Mobile Phase MeCN/H2O – 10/90% Buffer H2SO4 – 0.05 % Flow Rate 1.0 ml/min Detection UV, 200 nm
Description
Class of Compounds
Acid, Hydrophilic, Ionizable, Carboxylic acid, Drug, Carbocyclic, Amino acid Analyzing Compounds Carbocisteine, S-(Carboxymethyl)-L-cysteine
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
S-(Carboxymethyl)-L-cysteine
