Carbocisteine

CAS Number638-23-3
Molecular FormulaC5H9NO4S
Molecular Weight179.2
InChI KeyGBFLZEXEOZUWRN-VKHMYHEASA-N
LogP-3.1
Synonyms
  • S-Carboxymethyl-L-cysteine
  • 638-23-3
  • Carbocisteine
  • carbocysteine
  • carbocistein
  • S-(CARBOXYMETHYL)-L-CYSTEINE
  • Bronchokod
  • Mucolase
  • Mucotab
  • Siroxyl
  • Lisil
  • Mucodyne
  • (R)-S-(Carboxymethyl)cysteine
  • Carbocisteina
  • Carbocisteinum
  • S-(Carboxymethyl)-(R)-cysteine
  • L-3-((Carboxymethyl)thio)alanine
  • H-Cys(carboxymethyl)-OH
  • Transbronchin
  • Lisomucil
  • L-Carbocisteine
  • (L)-2-Amino-3-(carboxymethylthio)propionic acid
  • Mukinyl
  • Fluifort
  • Mucofan
  • Rinatiol
  • UNII-740J2QX53R
  • s-carboxymethyl-cysteine
  • Carboxymethylated Cysteine
  • MFCD00002614
  • 186537-58-6
  • S-Carboxymethylcysteine
  • Mucojet sirup
  • Mucolex sirup
  • Superthiol sirup
  • CHEMBL396416
  • CHEBI:16163
  • GBFLZEXEOZUWRN-VKHMYHEASA-N
  • 740J2QX53R
  • S-Carboxymethyl-L-cysteine, 98%
  • 3-(Carboxymethylthio)-L-alanine
  • Alanine, 3-((carboxymethyl)thio)-, L-
  • Carbocisteine-13C3
  • Chilvax
  • Mucosol
  • PectDrill
  • AHR 3053
  • LJ 206
  • C-1850
  • Carbocisteinum [INN-Latin]
  • Carbocisteina [INN-Spanish]
  • (2R)-2-amino-3-(carboxymethylthio)propanoic acid
  • (R)-2-Amino-3-((carboxymethyl)thio)propanoic acid
  • Q-200796
  • (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid
  • Pulmoclase
  • Carbocit
  • Mucolex
  • Mucopront
  • Mucotron
  • Pectox
  • AHR-3053
  • EINECS 211-327-5
  • L-(Carboxymethyl)cysteine
  • NSC 14156
  • SCMC
  • Carbocisteine [INN]
  • BRN 1725012
  • Carboxymethylenecysteine
  • L.J. 206
  • PSCMC
  • (R)-2-amino-3-(carboxymethylthio)propanoic acid
  • Poly(S-carboxymethylcysteine)
  • l-carbocysteine
  • Carbocysteine [USAN:INN:BAN]
  • Poly(S-carboxymethyl-L-cysteine)
  • L.J.206
  • Mucodyne (TN)
  • DF 1794Y
  • Carbocistein [JAN]
  • AC1L4WQH
  • L-Carbocisteine (JP17)
  • SCHEMBL20854
  • KSC495A3H
  • (2R)-2-Amino-3-[(carboxymethyl)thio]propionic acid
  • Jsp004777
  • CTK3J5033
  • (Carboxymethyl)cysteine-, (L)-
  • DTXSID30110060
  • 3-(Carboxymethylthio)alanine, L-
  • BCP13359
  • ZINC1529732
  • ANW-34746
  • BDBM50213735
  • LJ-206
  • SBB015059
  • AKOS015922826
  • 5-Amino-3-thiadihexanoic acid, (L)-
  • ACM2387599
  • DB04339
  • RL04429
  • RTC-066540
  • 29433-95-2
  • AC-11146
  • ACM186537586
  • AJ-26629
  • AK-81240
  • CC-25404
  • CC-34382
  • SC-19827
  • ST075001
  • AB1007076
  • AX8002883
  • DB-054558
  • ST2414447
  • TC-066540
  • FT-0082568
  • FT-0656306
  • FT-0658269
  • L-Cysteine, S-(carboxymethyl)-, homopolymer
  • KS-00001101
  • C03727
  • D00175
  • (2R)-2-amino-3-(carboxymethylthio)propionic acid
  • C-06527
  • 2-Amino-3-(carboxymethylthio)propionic acid, (L)-
  • I14-2712
  • I14-5234
  • (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid
  • UNII-4252LRM78Q component GBFLZEXEOZUWRN-VKHMYHEASA-N
  • (2R)-2-azanyl-3-(2-hydroxy-2-oxoethylsulfanyl)propanoic acid
  • Carbocisteine, European Pharmacopoeia (EP) Reference Standard
  • (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acidS-(carboxymethyl)-L-cysteine

Applications:

HPLC Separation of Mixture of Carbocisteine, Methylparaben & Propylparaben on Primesep 100 Column

July 31, 2019

HPLC Method for Carbocisteine, Methylparaben sodium, Propylparaben sodium, Propylparaben, Methylparaben on Primesep 100 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Carbocisteine, Methylparaben sodium, Propylparaben sodium, Propylparaben, Methylparaben.

Carbocysteine is a medication that reduces the viscosity of mucus making it easier to cough up. Methylparaben and propylparaben are used as preservatives in cosmetics, pharmaceuticals and food. They can be separated in HPLC on a Primesep 100 mixed-mode column by both hydrophobic and ionic properties present on the stationary phase. The analytical method uses acetonitrile (ACN) gradient and water with sulfuric acid (H2SO4) as buffer and UV detected at 200nm.

Condition

Column Primesep 100
Mobile Phase Gradient MeCN  – 2-50%, 20 min
Buffer H2SO4 – 0.05 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Drug,  Acid, Hydrophilic, Ionizable, Carboxylic acid, Carbocyclic, Benzoate, Hydroxy Acid, Amino Acid, Hydroxybenzoate, Phenol
Analyzing Compounds Carbocisteine, Methylparaben sodium, Propylparaben sodium, Propylparaben, Methylparaben

 

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Carbocisteine
Methylparaben
Methylparaben sodium
Propylparaben
Propylparaben sodium

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Determination of Carbocisteine on Primesep 100 Column

July 31, 2019

HPLC Method for Carbocisteine, S-(Carboxymethyl)-L-cysteine on Primesep 100 by SIELC Technologies

Carbocisteine

High Performance Liquid Chromatography (HPLC) Method for Analysis of Carbocisteine, S-(Carboxymethyl)-L-cysteine.

Carbocisteine, or carbocysteine, is a drug designed to clear the mucus from the upper and lower airways. It’s primarily available in tablet form. It can be retained on a Primesep 100 Column in about 5 minutes. Primesep 100 is a reverse-phase (RP) mixed-mode column with embedded acidic ion-pairing groups.

Condition

Column Primesep 100
Mobile Phase MeCN/H2O – 10/90%
Buffer H2SO4 – 0.05 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Acid, Hydrophilic, Ionizable, Carboxylic acid, Drug, Carbocyclic, Amino acid
Analyzing Compounds Carbocisteine, S-(Carboxymethyl)-L-cysteine

 

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Carbocisteine
S-(Carboxymethyl)-L-cysteine

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.