Aminocaproic acid

Aminocaproic acid structural formula

CAS Number60-32-2
Molecular FormulaC6H13NO2
Molecular Weight131.176
InChI KeySLXKOJJOQWFEFD-UHFFFAOYSA-N
LogP-2.95
Synonyms
  • 6-Aminocaproic acid
  • 6-Aminohexanoic acid
  • Hexanoic acid, 6-amino-
  • 60-32-2
  • Hexanoic acid, 6-amino-
  • 6-Aminohexanoic acid
  • 6-Amino-n-hexanoic acid
  • Acepramin
  • Acepramine
  • Acide aminocaproique
  • acido aminocaproico
  • Acikaprin
  • Afibrin
  • aminocaproic acid
  • Aminocapronsaure
  • Aminokapron
  • Caplamin
  • Capramol
  • Caprocid
  • Caproic acid, ε-amino-
  • Caprolisin
  • Epsamon
  • Epsicapron
  • Epsikapron
  • Epsilcapramin
  • Epsilon S
  • EPSILON-AMINOCAPRONSAEURE
  • Hemocaprol
  • Hemopar
  • Ipsilon
  • NSC 212532
  • NSC 26154
  • NSC 400230
  • Respramin
  • ε-Aminocaproic acid
  • ε-Aminohexanoic acid
  • ε-Amino-n-hexanoic acid
  • ε-Leucine
  • ε-Norleucine
  • ω-Aminocaproic acid
  • ω-Aminohexanoic acid
  • BRN 0906872
  • Capralense
  • Eaca kabi
  • EINECS 200-469-3
  • NSC-26154
  • omega-Aminocaproic acid
  • Epsilon-aminocapronzuur
  • Aminocaproic
  • Aminocaproic acid in plastic container
  • Kyselina omega-aminokapronova
  • UNII-U6F3787206
  • Epsilon Aminocaproic Acid
  • 6-Amino-Hexanoate
  • 6-Amino-Hexanoic acid
  • 6-Amino-N-hexanoate
  • 6-Aminocaproate
  • 6-Aminohexanoate
  • Ahx
  • Amikar
  • Atsemin
  • Capracid
  • Capranol
  • EACA
  • Epsillon-Aminocaproate
  • Epsillon-Aminocaproic acid
  • Epsillon-Aminocaproic acid' Epsilcapramin
  • H-6-Ahx-OH
  • H-EAhx-OH
  • H-epsilon-Acp-OH
  • Hepin
  • Omega-Aminocaproate
  • Omega-Aminohexanoate
  • Z
  • aminohexanoic acid
  • e-Amino-N-hexanoate
  • e-Amino-N-hexanoic acid
  • e-Aminocaproate
  • e-Aminocaproic acid
  • e-Aminocaproic acid USP
  • e-Aminohexanoate
  • e-Aminohexanoic acid
  • e-Leucine
  • e-Norleucine
  • epsilon-Ahx
  • epsilon-Amino-N-hexanoate
  • epsilon-Aminocaproate
  • epsilon-Aminocaproic acid USP
  • epsilon-Aminohexanoate
  • epsilon-S
  • epsilon-amino-n-hexanoic acid
  • epsilon-aminocaproic acid
  • epsilon-aminohexanoic acid
  • epsilon-leucine
  • epsilon-norleucine
  • omega-aminocaproic acid
  • omega-aminohexanoic acid
  • w-Aminocaproate
  • w-Aminocaproic acid
  • w-Aminohexanoate
  • w-Aminohexanoic acid
  • 6-ammoniohexanoate
  • 6-aminohexanoic acid zwitterion
  • 87867-96-7
  • 93208-38-9

Applications:

HPLC Determination of 6-Aminocaproic Acid With Low UV Detection

2020-05-22
HPLC.cloud View on hplc.cloud 6-aminocaproic Acid, brand name Amicar, is a clotting agent used to control excessive bleeding in patients during or after surgery by acting as an inhibitor to fibrinolysis. It can be retained using HPLC on Newcrom AH mixed-mode column using isocratic analysis with mobile phase consisting of acetonitrile and water (ACN/H2O) with sulfuric acid (H2SO4) as buffer and detected at low UV of 200 nm.

Condition

Column Newcrom АH, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 50/50%
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV 200 nm

Description

Class of Compounds Acid
Analyzing Compounds 6-Aminocaproic Аcid
SIELC Technologies usually develops more than one method for each compound on our website. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound of interest.
Application Analytes:
Aminocaproic acid

HPLC Determination of 6-Aminocaproic Аcid on Newcrom A Column

2020-05-21
HPLC.cloud View on hplc.cloud 6-aminocaproic Acid, brand name Amicar, is a clotting agent used to control excessive bleeding in patients during or after surgery by acting as an inhibitor to fibrinolysis. It can be retained using HPLC and low capacity Newcrom A mixed-mode column using isocratic analysis with mobile phase consisting of acetonitrile and water (ACN/H2O) and MS-compatible ammonium formate (AmFm) buffer.

Condition

Column Newcrom А, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/90%
Buffer Ammonium Formate pH 3.0 - 10 мМ
Flow Rate 1.0 ml/min
Detection CAD, Corona (MS-compatible mobile phase)

Description

Class of Compounds Acid
Analyzing Compounds 6-Aminocaproic Аcid
SIELC Technologies usually develops more than one method for each compound on our website. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound of interest.
Application Analytes:
Aminocaproic acid

USP Methods for the Analysis of Aminocaproic Acid using the Legacy L1 Column

2012-06-21
  Application Notes: Aminocaproic acid is a enzymatic inhibitor. According to USP methods, aminocaproic acid conatins not less than 98.5% and not more than 101.5% of aminocaproic acid calculated on a dried basis. The USP HPLC method for the separation of aminocaproic acid was developed on Legacy L1 column according to the US Pharmacopeia methodology. L1 classification is assigned to reversed-phase HPLC column containing C18 ligand. Support for the material is spherical silica gel with particles size 3-10 um and pore size of 100-120A. Resolution between critical pairs corresponds to rules and specifications of UPS.   Application Columns: Legacy L1 C18 HPLC column Application compounds: Aminocaproic acid Mobile phase: Sodium heptanesulfonate/H2O/MeOH /NaH2PO4 pH 2.2 Detection technique: UV Reference: USP35: NF30

Condition

Column Legacy L1, 4.6x150 mm, 5 µm, 100A
Mobile Phase Sodium heptanesulfonate/H2O/MeOH /NaH2PO4 pH 2.2
Flow Rate 0.7 ml/min
Detection UV, 210 nm
 

Description

Class of Compounds Drug, Clotting promoter, Hydrophilic, Ionizable
Analyzing Compounds Aminocaproic Acid
 
SIELC Technologies usually develops more than one method for each compound on our website. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound of interest.
Application Analytes:
Aminocaproic acid

Application Detection:
UV Detection