6-aminocaproic Acid, brand name Amicar, is a clotting agent used to control excessive bleeding in patients during or after surgery by acting as an inhibitor to fibrinolysis. It can be retained using HPLC on Newcrom AH mixed-mode column using isocratic analysis with mobile phase consisting of acetonitrile and water (ACN/H2O) with sulfuric acid (H2SO4) as buffer and detected at low UV of 200 nm.
| Column | Newcrom АH, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O – 50/50% |
| Buffer | H2SO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 200 nm |
| Class of Compounds | Acid |
| Analyzing Compounds | 6-Aminocaproic Аcid |
Application Column
Newcrom AH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsApplication Analytes:
6-Aminocaproic acid
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