CAS Number | 55-63-0 |
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Molecular Formula | C3H5N3O9 |
Molecular Weight | 227.086 |
InChI Key | SNIOPGDIGTZGOP-UHFFFAOYSA-N |
LogP | 1.62 |
Synonyms |
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Applications:
HPLC Method for Analysis of Nitroglycerin on Newcrom R1 Column
June 7, 2018
HPLC Method for Nitroglycerin on Newcrom R1 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Nitroglycerin
Nitroglycerin is a chemical compound with C3H5N3O9 as it’s molecular formula. Historically, Nitroglycerin has been used as an explosive. These days, however, it is more commonly used as a vasodilator medication through widening blood vessels.
Nitroglycerin can be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a phosphoric acid buffer. Detection is performed using UV.
Column | Newcrom R1, 4.6 x 100 mm, 5 µm, 100 A, dual ended |
Mobile Phase | MeCN/H2O – 50/50% |
Buffer | H3PO4 – 0.1 % |
Flow Rate | 1.0 ml/min |
Detection | UV, 215 nm |
Class of Compounds | Drug, Basic, Hydrophobic, Ionizable, Vasodilator |
Analyzing Compounds | Nitroglycerin |
Application Column
Newcrom R1
Column Diameter: 4.6 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended