p-coumaric acid

CAS Number501-98-4
Molecular Formula C9H8O3
Molecular Weight164.16
InChI KeyNGSWKAQJJWESNS-ZZXKWVIFSA-N
LogP1.5
Synonyms
  • p-coumaric acid
  • 4-Hydroxycinnamic acid
  • 501-98-4
  • p-Hydroxycinnamic acid
  • 4-Coumaric acid
  • trans-4-Hydroxycinnamic acid
  • 7400-08-0
  • trans-p-Coumaric acid
  • p-Cumaric acid
  • Para-Coumaric acid
  • 3-(4-hydroxyphenyl)acrylic acid
  • Hydroxycinnamic acid
  • Naringeninic acid
  • p-Hydroxy-cinnamic acid
  • (E)-p-Coumaric acid
  • trans-p-Coumarinic acid
  • 4'-hydroxycinnamic acid
  • 2-propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-
  • 4-coumarate
  • p-Hydroxyphenylacrylic acid
  • (E)-p-Hydroxycinnamic acid
  • trans-p-Hydroxycinnamic acid
  • Cinnamic acid, p-hydroxy-
  • trans-4-coumaric acid
  • (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid
  • 3-(4-Hydroxyphenyl)-2-propenoic acid
  • trans-p-Hydroxycinnamate
  • 4-Hydroxycinnamate
  • 2-Propenoic acid, 3-(4-hydroxyphenyl)-
  • (E)-3-(4-hydroxyphenyl)prop-2-enoic acid
  • (E)-3-(4-Hydroxyphenyl)-2-propenoic acid
  • 3-(4-hydroxyphenyl)prop-2-enoic acid
  • trans-4-hydroxycinnamate
  • (2E)-3-(4-hydroxyphenyl)acrylic acid
  • (E)-3-(4-Hydroxyphenyl)acrylic acid
  • UNII-IBS9D1EU3J
  • beta-(4-Hydroxyphenyl)acrylic acid
  • Cinnamic acid, p-hydroxy-, (E)-
  • Para coumaric acid
  • (E)-4-hydroxycinnamic acid
  • trans-p-Cumaric Acid
  • 4-Hydroxycinamic acid

Applications:

HPLC Separation of Phenolic Acids

March 11, 2021


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Condition 1

Column Newcrom B, 4.6×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN
Buffer H3PO4 – 0.2%
Flow Rate 1.0 ml/min
Detection 270 nm

Condition 2

Column Newcrom R1, 4.6×150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN
Buffer H3PO4 – 0.2%
Flow Rate 1.0 ml/min
Detection 270 nm

Description

Class of Compounds Acid
Analyzing Compounds Gallic acid, 3,4 Dihydroxybenzoic acid, Caffeic acid, trans-Ferulic acid, trans- p -Coumaric acid, trans-Cinnamic acid, Quercetin Hydrate, Salicylic acid

 

Application Column

Newcrom B

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
3,4-Dihydroxybenzoic Acid
Caffeic acid
Cinnamic acid
Ferulic acid
Gallic acid
Quercetin
Quercetin dihydrate
Salicylic acid
p-coumaric acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of Coumaric acids on Newcrom BH Column

January 27, 2021


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p-Coumaric acid is the major phenolic acid in a wide variety of graminaceous plants.  p-Coumaric acid is a natural metabolite contained in many edible plants and its antioxidant activities in reducing oxidative stress and inflammatory reactions have been demonstrated in various experiments  The three isomers of coumaric acid can be detected at low UV.  Using Newcrom BH mixed-mode column and a mobile phase consisting of acetonitrile (ACN), and water with phosphoric acid (H3PO4) buffer, the acids can be retained and UV detected at 270nm.

Condition

Column Newcrom BH, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer H3PO4 – 1.0%
Flow Rate 1.0 ml/min
Detection 270 nm

Description

Class of Compounds Acid
Analyzing Compounds p -Coumaric Acid, .m -Coumaric Acid, o -Coumaric Acid

 

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
m-Coumaric acid
o-coumaric acid
p-coumaric acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.