m-Coumaric acid

Molecular FormulaC9H8O3
Molecular Weight164.16
LogP1.8
Synonyms
  • 3-Hydroxycinnamic acid
  • 14755-02-3
  • M-COUMARIC ACID
  • 3-Coumaric acid
  • 588-30-7
  • m-Hydroxycinnamic acid
  • trans-3-Hydroxycinnamic acid
  • trans-3-Hydroxycinnamate
  • (E)-3-(3-Hydroxyphenyl)acrylic acid
  • 3-(3-Hydroxyphenyl)acrylic acid
  • (2E)-3-(3-hydroxyphenyl)acrylic acid
  • Cinnamic acid, m-hydroxy-
  • trans-m-Coumaric Acid
  • trans-3-coumaric acid
  • 2-propenoic acid, 3-(3-hydroxyphenyl)-, (2E)-
  • (2E)-3-(3-hydroxyphenyl)prop-2-enoic acid
  • (E)-3-(3-hydroxyphenyl)prop-2-enoic acid
  • (E)-3-(3-Hydroxyphenyl)-2-propenoic acid
  • 3'-Hydroxycinnamic acid
  • UNII-KWJ2DDJ34H
  • 2-Propenoic acid, 3-(3-hydroxyphenyl)-
  • (2E)-3-(3-Hydroxyphenyl)-2-propenoic acid
  • MFCD00004390
  • NSC 28956
  • NSC 50308
  • KWJ2DDJ34H
  • 3-(3-hydroxyphenyl)-2-propenoic acid
  • 3-(3-hydroxyphenyl)prop-2-enoic acid
  • CHEMBL98521
  • 3-(3-Hydroxyphenyl)acrylsaeure
  • CHEBI:32357
  • 2-Propenoic acid, 3-(3-hydroxyphenyl)-, (E)-
  • m-Coumarate

Applications:

HPLC Separation of Coumaric acids on Newcrom BH Column

January 27, 2021

HPLC Method for m-Coumaric acid, o-coumaric acid, p-coumaric acid on Newcrom BH by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of m-Coumaric acid, o-coumaric acid, p-coumaric acid.

p-Coumaric acid is a major phenolic acid with the chemical formula C9H8O3. It can be found in a wide variety of graminaceous plants.  p-Coumaric acid is a natural metabolite contained in many edible plants and its antioxidant activities in reducing oxidative stress and inflammatory reactions have been demonstrated in various experiments.

m-Coumaric acid is a hydroxycinnamic acid with the chemical formula C9H8O3. It can be found in a vinegar.  It differs from p-Coumaric acid in the position of the hydroxy substitution.

o-Coumaric acid is a hydroxycinnamic acid with the chemical formula C9H8O3. It can be found in a vinegar.  It differs from p-Coumaric acid and m-Coumaric acid in the position of the hydroxy substitution.

The three isomers of coumaric acid, m-Coumaric acid, o-coumaric acid, p-coumaric acid, can be detected at low UV.  Using Newcrom BH mixed-mode column and a mobile phase consisting of acetonitrile (ACN), and water with phosphoric acid (H3PO4) buffer, the acids can be retained and UV detected at 270nm.

Condition
Column Newcrom BH, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 20/80%
Buffer H3PO4 – 1.0%
Flow Rate 1.0 ml/min
Detection 270 nm

Description
Class of Compounds Acid
Analyzing Compounds m-Coumaric acid, o-coumaric acid, p-coumaric acid

 

Application Column

Newcrom BH

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
m-Coumaric acid
o-coumaric acid
p-coumaric acid
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.