o-coumaric acid

CAS Number614-60-8
Molecular FormulaC9H8O3
Molecular Weight164.16
InChI KeyPMOWTIHVNWZYFI-AATRIKPKSA-N
LogP1.5
Synonyms
  • 2-Hydroxycinnamic acid
  • 614-60-8
  • o-Coumaric acid
  • trans-2-Hydroxycinnamic acid
  • 2-Coumaric acid
  • trans-o-Coumaric acid
  • trans-o-Hydroxycinnamic acid
  • 2-Hydroxycinnamate
  • 2-Coumarate
  • (E)-o-Hydroxycinnamic acid
  • trans-2-Hydroxycinnamate
  • (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid
  • o-Hydroxy-trans-cinnamic acid
  • 3-(2-hydroxyphenyl)acrylic acid
  • (E)-3-(2-Hydroxyphenyl)-2-propenoic acid
  • (2E)-3-(2-HYDROXYPHENYL)ACRYLIC ACID
  • 2-Hydroxycinamic acid
  • 583-17-5
  • (E)-3-(2-hydroxyphenyl)prop-2-enoic acid
  • trans-2-coumaric acid
  • (2E)-3-(2-Hydroxyphenyl)-2-propenoic acid
  • 2-Hydroxycinnamic acid, (E)-
  • CINNAMIC ACID, o-HYDROXY-, (E)-
  • UNII-23AU5FZB9C
  • (E)-2-hydroxycinnamic acid
  • CCRIS 5834
  • 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (2E)-
  • trans-ortho-coumaric acid
  • EINECS 210-386-4
  • NSC 32952
  • 2-Propenoic acid, 3-(2-hydroxyphenyl)-, (E)-
  • BRN 1100900
  • 23AU5FZB9C
  • (2E)-2-hydroxycinnamic acid
  • 2-Propenoic acid, 3-(2-hydroxyphenyl)-
  • CHEMBL52564
  • 2-Hydroxycinnamic acid, predominantly trans
  • CHEBI:18125
  • 3-(2-hydroxyphenyl)prop-2-enoic acid
  • o-coumarate
  • MFCD00004379
  • (E)-3-(2-hydroxyphenyl)acrylic acid
  • 2-Hydroxy Cinnamic Acid
  • (E)-3-(2-HYDROXY-PHENYL)-ACRYLIC ACID
  • 3-(2-hydroxyphenyl)prop-2-enoate
  • cis-2-hydroxycinnamic acid
  • o-Hydroxycinnamate
  • 3-(2-Hydroxyphenyl)-2-propenoic acid
  • trans-o-Coumarate
  • (2Z)-3-(2-hydroxyphenyl)acrylic acid
  • ortho-Hydroxycinnamate
  • PubChem8214
  • (E)-Coumarinic Acid
  • (2Z)-3-(2-hydroxyphenyl)acrylate
  • trans-o-Hydroxycinnamate
  • (E)-ortho-coumaric acid
  • o-Hydroxy-trans-cinnamate
  • (E)-o-Hydroxycinnamicacid
  • bmse000347
  • Cinnamic acid, o-hydroxy-
  • WLN: QV1U1R BQ
  • SCHEMBL64885
  • QSPL 150
  • CHEBI:18176
  • trans-o-HydroxyzimtsA currencyure
  • 2-Hydroxycinnamic acid, (2E)-

Applications:

HPLC Separation of Coumaric acids on Newcrom BH Column

January 27, 2021


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p-Coumaric acid is the major phenolic acid in a wide variety of graminaceous plants.  p-Coumaric acid is a natural metabolite contained in many edible plants and its antioxidant activities in reducing oxidative stress and inflammatory reactions have been demonstrated in various experiments  The three isomers of coumaric acid can be detected at low UV.  Using Newcrom BH mixed-mode column and a mobile phase consisting of acetonitrile (ACN), and water with phosphoric acid (H3PO4) buffer, the acids can be retained and UV detected at 270nm.

Condition
Column Newcrom BH, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer H3PO4 – 1.0%
Flow Rate 1.0 ml/min
Detection 270 nm

Description
Class of Compounds Acid
Analyzing Compounds p -Coumaric Acid, .m -Coumaric Acid, o -Coumaric Acid

 

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
m-Coumaric acid
o-coumaric acid
p-coumaric acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.