Methyl methanesulfonate

Methyl methanesulfonate structural formula

CAS Number66-27-3
Molecular FormulaC2H6O3S
Molecular Weight110.130
  • Methyl methanesulfonate
  • Methanesulfonic acid, methyl ester
  • 66-27-3
  • MMS
  • 4-04-00-00011
  • Methanesulfonic acid, methyl ester
  • metanosulfonato de metilo
  • Methanesulfonate de methyle
  • methyl methanesulphonate
  • Methyl methylsulfonate
  • Methylmethansulfonat
  • NSC 50256
  • BRN 1098586
  • as-Dimethyl sulphite
  • EINECS 200-625-0
  • Methanesulphonic acid methyl ester
  • Methyl ester of methanesulfonic acid
  • Methyl ester of methanesulphonic acid
  • Methyl methanesulfonic acid
  • Methyl methansulfonate
  • Methyl methansulphonate
  • Methylmethane sulfonate
  • Methylmethanesulfonate
  • Methylmethanesulphonate
  • NSC-50256
  • Methylester kyseliny methansulfonove
  • UNII-AT5C31J09G
  • CB1540
  • Methanesulfonic acid methyl ester
  • Methyl mesylate
  • as-Dimethyl sulfite


Separation of Methyl methanesulfonate on Newcrom R1 HPLC column

Separation of Methyl methanesulfonate on Newcrom C18 HPLC column

Methyl methanesulfonate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail:" or by phone: 847-229-2629.
SIELC Technologies usually develops more than one method for each compound on our website. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to so we can ensure you get optimal results for your compound of interest.
Application Analytes:
Methyl methanesulfonate