HPLC Determination of Oseltamivir on Primesep 100 Column

Separation type: Liquid Chromatography Mixed-mode




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High Performance Liquid Chromatography (HPLC) Method for Analysis of Oseltamivir




Oseltamivir belongs to a class of drugs called antivirals, which are used to treat infections caused by viruses. Oseltamivir is used in the treatment of the infection caused by the flu virus (influenza A and influenza B). Oseltamivir may also be used to prevent and treat swine influenza A. Valacyclovir can be retained on a Primesep 100 column with great peak shape using an isocratic method of acetonitrile (ACN), water and sulphuric acid (H2SO4) as a buffer. UV Detection 200nm.



Condition
Column Primesep 100, 3.2×100 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 30/70%
Buffer H2SO4 – 0.5%
Flow Rate 0.5 ml/min
Detection UV, 200 nm

 

Description
Class of Compounds
 Drug
Analyzing Compounds Oseltamivir

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Application Analytes:
Oseltamivir
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.