HPLC Determination of Meloxicam on Newcrom R1 Column

HPLC Method for Meloxicam on Newcrom R1 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Meloxicam.

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) with the chemical formula C14H13N3O4S2. It is reported to have antipyretic and analgesic activities. Meloxicam can result in gastrointestinal bleeding, headaches, rashes, and other toxic side effects. In certain countries, it is also widely used for veterinary cases.

Meloxicam can be retained in HPLC on Newcrom R1 column with the simple isocratic mobile phase consisting of acetonitrile (MeCN) and water with sulfuric acid (H2SO4) buffer. The analysis method can be UV detected at 362nm.

Condition

Column Newcrom R1, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN – 50%
Buffer H2SO4 – 0.1%
Flow Rate 1.0 ml/min
Detection 362 nm

Description

Class of Compounds Drug, Hydrophobic
Analyzing Compounds Meloxicam

 

Application Column

Newcrom R1

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Meloxicam

Application Detection:
UV Detection
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