| CAS Number | 38677-85-9 |
|---|---|
| Molecular Formula | C14H11F3N2O2 |
| Molecular Weight | 296.24 |
| InChI Key | NOOCSNJCXJYGPE-UHFFFAOYSA-N |
| LogP | 4.1 |
| Synonyms |
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Applications:
HPLC Method for Determination of Flunixin and Meglumine on Primesep 100 Column
September 27, 2022
HPLC Method for Meglumine (N-Methyl-D-glucamine), Flunixin on Primesep 100 by SIELC Technologies
Flunixin is an analgesic and antipyretic nonsteroidal anti-inflammatory drug (NSAID) with the chemical formula C14H11F3N2O2. It is used primarily by veterinarians in bovine and equine treatments. Prolonged consecutive use can cause health problems due to toxicity. Due to that, it is a prohibited substance under International Federation for Equestrian Sports rules. It is typically produced as a Meglumine salt, which helps stabilize and bulk up the medication in its solid form. You can find detailed UV spectra of Flunixin and information about its various lambda maxima by visiting the following link.
Meglumine is a sugar alcohol with the chemical formula C7H17NO5. It is a derivative of glucose that is used primarily as an excipient in pharmaceuticals. You can find detailed UV spectra of Meglumine and information about its various lambda maxima by visiting the following link.
Meglumine (N-Methyl-D-glucamine), Flunixin can be retained, separated, and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple isocratic mobile phase of water, Acetonitrile (MeCN), and a sulfuric acid (H2SO4) buffer. This analysis method can be UV detected at 252 nm (Flunixin) with high resolution and peak symmetry and is compatible with Mass Spectrometry (MS), ELSD, and CAD.
| Column | Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN – 60% |
| Buffer | TFA – 0.2% |
| Flow Rate | 1.0 ml/min |
| Detection | ELSD, 50C, UV 252 nm |
| Class of Compounds | Drug |
| Analyzing Compounds | Meglumine (N-Methyl-D-glucamine), Flunixin |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Meglumine (N-Methyl-D-glucamine)
ELSD Detection
HPLC Method for Determination of Flunixin on Primesep 100 Column
September 21, 2022
HPLC Method for Flunixin on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Flunixin
Flunixin is an analgesic and antipyretic nonsteroidal anti-inflammatory drug (NSAID) with the chemical formula C14H11F3N2O2. It is used primarily by veterinarians in bovine and equine treatments. Prolonged consecutive use can cause health problems due to toxicity. Due to that, it is a prohibited substance under International Federation for Equestrian Sports rules. It is typically produced as a Meglumine salt, which helps stabilize and bulk up the medication in its solid form. You can find detailed UV spectra of Flunixin and information about its various lambda maxima by visiting the following link.
Flunixin can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a sulfuric acid buffer. Detection is performed using UV.
| Column | Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN – 60% |
| Buffer | H2SO4 – 0.2% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 252 nm |
| Class of Compounds | Drug |
| Analyzing Compounds | Flunixin |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
