CAS Number | 23031-25-6 |
---|---|
Molecular Formula | C12H19NO3 |
Molecular Weight | 225.288 |
InChI Key | XWTYSIMOBUGWOL-UHFFFAOYSA-N |
LogP | 0.9 |
Synonyms |
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Applications:
UV-Vis Spectrum of Terbutaline
July 19, 2024
UV-Vis Spectrum of Terbutaline. Absorption Maxima: 200 nm, 280 nm.
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
HPLC Method for Separation of Terbutaline Sulfate, Guaifenesin and Ambroxol on Primesep 200 Column
January 12, 2023
High Performance Liquid Chromatography (HPLC) Method for Separation of Terbutaline Sulfate, Guaifenesin and Ambroxol on Primesep 200 by SIELC Technologies
Separation type: Liquid Chromatography Mixed-mode
![HPLC Method for Separation of Terbutaline Sulfate, Guaifenesin and Ambroxol on Primesep 200 Column](https://sielc.com/wp-content/uploads/2023/01/HPLC-Method-for-Separation-of-Terbutaline-Sulfate-Guaifenesin-and-Ambroxol-on-Primesep-200-Column_1550.png)
Terbutaline Sulfate is a β2 analyst typically used as a prescription-strength cough suppressant. Guaifenesin, also known as Glyceryl Guaiacolate, is a popular expectorant used to treat chest congestion. Ambroxol is a well-known expectorant that targets and breaks down phlegm. Together, these three medicinal compounds are typically found as the active ingredients in many cough syrups. They can be retained, analyzed, and separated on a Primesep 200 mixed-mode column using an isocratic analytical method with a simple mobile phase of water, Acetonitrile (MeCN), and a Phosphoric acid (H3PO4) ionic modifier. This analysis method can be detected in the low UV regime at 210 nm.
High Performance Liquid Chromatography (HPLC) Method for Separation of Terbutaline Sulfate, Guaifenesin and Ambroxol
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Condition
Column | Primesep 200, 4.6×150 mm, 5 µm, 100A |
Mobile Phase | MeCN/H2O – 30/70% |
Buffer | H3PO4 – 0.05% |
Flow Rate | 1.0 ml/min |
Detection | UV 210 nm |
Peak Retention Time | 2.09, 3.28, 5.81 min |
Description
Class of Compounds | Drugs |
Analyzing Compounds | Terbutaline Sulfate, Guaifenesin and Ambroxol |
Application Column
Primesep 200
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Guaifenesin
Terbutaline
HPLC Separation of Guaifenesin and Terbutaline on Primesep 200
June 5, 2006
Application Column
Primesep 200
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Terbutaline
HPLC Separation of Guaifenesin and Terbutaline on Primesep 100
June 5, 2006
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Terbutaline