Trilostane

Trilostane structural formula

CAS Number13647-35-3
Molecular FormulaC20H27NO3
Molecular Weight329.441
InChI KeyKVJXBPDAXMEYOA-CXANFOAXSA-N
LogP2.80
Synonyms
  • Trilostane
  • (4alpha,5alpha,17beta)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile
  • Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4alpha,5alpha,17beta)-
  • 13647-35-3
  • Androstane-2-carbonitrile, 4,5-epoxy-17-hydroxy-3-oxo-, (2-alpha,4-alpha,5-alpha,17-beta)-
  • EINECS 237-133-0
  • 4-alpha,5-Epoxy-3,17-dihydroxy-5-alpha-androst-2-ene-2-carbonitrile
  • (2-alpha,4-alpha,5-alpha,17-beta)-4,5-Epoxy-17-hydroxy-3-oxoandrostane-2-carbonitrile
  • 4-alpha-5-Epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitrile
  • Modrenal
  • Modrastane
  • Trilostano
  • Trilostanum
  • UNII-L0FPV48Q5R
  • Vetoryl

Applications:

HPLC Method for Analysis of Trilostane

September 28, 2018

Condition
Column Newcrom R1, 4.6×100 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer Na2HPO4 pH 6.5 – 10 mM
Flow Rate 1.0 ml/min
Detection UV, 252 nm

 

Description
Class of Compounds
 Drug,  Hydrophobic, Ionizable, Zwitterionic, Steroidogenesis inhibitor
Analyzing Compounds Trilostane

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Trilostane
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