Quetiapine

CAS Number111974-69-7
Molecular FormulaC21H25N3O2S
Molecular Weight383.511
InChI KeyURKOMYMAXPYINW-UHFFFAOYSA-N
LogP2.09
Synonyms
  • Quetiapine
  • 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy}ethan-1-ol
  • Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-
  • 111974-69-7
  • Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-
  • UNII-BGL0JSY5SI
  • Co-Quetiapine
  • 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
  • 2-[2-(4-{2-thia-9-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}piperazin-1-yl)ethoxy]ethan-1-ol
  • Quetiapine
  • Quetiapine fumarate
  • Seroquel

Applications:

HPLC Method for Analysis of Quetiapine in Tablets on Newcrom R1 Column

June 7, 2018

HPLC Method for Analysis of Quetiapine in Tablets_Chr_1134

 

Condition
Column Newcrom R1, 4.6×100 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer TEAPh – 50 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm

 

Description
Class of Compounds
 Drug, Antipsychotic, Hydrophobic, Neutral
Analyzing Compounds Quetiapine

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Quetiapine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.