Pentachlorophenol

Pentachlorophenol structural formula

CAS Number87-86-5
Molecular FormulaC6HCl5O
Molecular Weight266.321
InChI KeyIZUPBVBPLAPZRR-UHFFFAOYSA-N
LogP5.12
Synonyms
  • Pentachlorophenol
  • Phenol, 2,3,4,5,6-pentachloro-
  • 87-86-5
  • PCP
  • 2,3,4,5,6-Pentachlorophenol
  • Phenol, pentachloro-
  • 1-Hydroxy-2,3,4,5,6-pentachlorobenzene
  • 1-Hydroxypentachlorobenzene
  • Chlorophenasic acid
  • CHLOROPHENATE
  • Dowicide EC 7
  • Dura Treet II
  • Fungifen
  • Grundier Arbezol
  • Lauxtol
  • Liroprem
  • NSC 263497
  • Penchlorol
  • Pentachlorphenol
  • Perchlorophenol
  • Permasan
  • Phenol, 2,3,4,5,6-pentachloro-
  • Pole topper
  • Pole topper fluid
  • Preventol P
  • Santophen 20
  • Satophen
  • UN 3155
  • Witophen P
  • Woodtreat A
  • BRN 1285380
  • Caswell No. 641
  • Chem-Penta
  • Dow pentachlorophenol DP-2 antimicrobial
  • Dowicide 7 Antimicrobial
  • Dowicide EC-7
  • EINECS 201-778-6
  • EPA Pesticide Chemical Code 063001
  • Forpen-50 Wood Preservative
  • NCI-C54933
  • NCI-C55378
  • NCI-C56655
  • Ontrack WE Herbicide
  • Ortho Triox Liquid Vegetation Killer
  • Osmose Wood Preserving Compound
  • Penta Concentrate
  • Penta ready
  • Penta WR
  • Pentachlorofenol
  • Pentachlorophenol, DP-2
  • Permatox DP-2
  • Permatox penta
  • RCRA waste number U242
  • Watershed Wood Preservative
  • Weed and Brush Killer
  • Pentachloorfenol
  • Pentaclorofenolo
  • UNII-D9BSU0SE4T
  • 2, 3,4,5,6-Pentachlorophenol
  • 2,3,4,5,6-Pentachlorophenol (ACD/Name 4.0)
  • Chem-Tol
  • Chlorophen
  • Dowicide 7
  • Dowicide G
  • Durotox
  • Fungifen
  • Glazd penta
  • Lauxtol A
  • PCP (pesticide)
  • Penta
  • Penta-Kil
  • Pentachloorfenol (DUTCH)
  • Pentachloro-Phenol
  • Pentachlorophenate
  • Pentachlorophenol pure
  • Pentachlorphenol (GERMAN)
  • Pentaclorofenolo (ITALIAN)
  • Pentacon
  • Pentasol
  • Penwar
  • Peratox
  • Permacide
  • Permagard
  • Permatox
  • Permite
  • Phenol, pentachloro-, pure
  • Santobrite
  • Santophen
  • Sinituho
  • Term-i-trol
  • Thompson'S wood fix
  • Weedone
  • 101802-54-4
  • 1135443-67-2
  • 39390-77-7

Applications:

HPLC Separation of Haloaromatics and Quinones on Newcrom B Column

February 6, 2020

HPLC Method for Benzoquinone, Hydroquinone, Chlorothalonil, Chloranil, Pentachlorophenol, Tetrachlorohydroquinone on Newcrom B by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Benzoquinone, Hydroquinone, Chlorothalonil, Chloranil, Pentachlorophenol, Tetrachlorohydroquinone.

1,4-benzoquinone, also known as para-quinone, is a compound with the formula C6H4O2. It is typically used as a precursor to hydroquinone, which is a reducing agent and antioxidant. It also serves as a dehydrogenation reagent and dienophile in Diels-Alder reactions.

1,4-hydroquinone is an aromatic derivative of benzene with the chemical formula C6H6O2. It is often used in skin whitening, although it has been banned by the United States Food and Drug Administration for over-the-counter use due to being a potential carcinogen. It can cause a variety of disease including but not limited to ochronosis. thyroid follicular cell hyperplasias, mononuclear cell leukemia, and adenomas. Agencies across the world encourage research into other agents to treat hyperpigmentation. You can find detailed UV spectra of hydroquinone and information about its various lambda maxima by visiting the following link.

Chloranil, also known as tetrachloro-1,4-benzoquinone, is a quinone with the chemical formula C6Cl4O2. It is a planar molecule that functions as an oxidant. It serves as a hydrogen acceptor and is more electrophilic than quinone.  Chloranil is used to test for free secondary amines, which is useful to check for the presence of proline derivatives. Commercially, it is a precursor to dyes.

Chlorothalonil is a compound with a variety of uses as a fungicide, wood protectant, pesticide, and acaricide. It is used predominantly on peanuts, potatoes, and tomatoes. Outside of agriculture, it is also used in paints, resins, emulsions, and coatings. It’s chemical formula is C8Cl4N2.

Tetrachlorohydroquinone, also known as TCHQ, is a chlorinated organic compound with the chemical formula C6H2Cl4O2. It is a metabolote of the biocide pentachlorophenol. It causes damage to cells by increasing reactive oxygen species (ROS). It is harmful if swallowed and can cause serious eye damage.

Pentachlorophenol is a manufactured chemical with the chemical formula C6HCl5O. It is most often used as herbicide, insecticide, fungicide, algaecide, and disinfectant. Exposure to it can cause damage to liver, kidney, blood, lungs, eyes, skin, and mouth. It is classified as a probable human carcinogen.

Benzoquinone, Hydroquinone, Chlorothalonil, Chloranil, Pentachlorophenol, Tetrachlorohydroquinone can be retained and analyzed using the Newcrom B stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a phosphoric acid buffer. Detection is performed using UV.

Condition

Column Newcrom B, 4.6 x 150 mm, 3 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 55/45%
Buffer H3PO4 – 0.1%
Flow Rate 1.0 ml/min
Detection UV 200 nm

 

Description

Class of Compounds Haloaromatics, Quinones, Hydrophobic
Analyzing Compounds Benzoquinone, Hydroquinone, Chlorothalonil, Chloranil, Pentachlorophenol, Tetrachlorohydroquinone

Application Column

Newcrom B

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Benzoquinone
Chloranil
Chlorothalonil
Hydroquinone
Pentachlorophenol
Tetrachlorohydroquinone

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of Pesticides on Newcrom B Column

February 3, 2020

HPLC Method for Metalaxyl (UV), Propoxur, Paclobutrazol, Abamectin, Propanil, Iprodione, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate on Newcrom B by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Metalaxyl (UV), Propoxur, Paclobutrazol, Abamectin, Propanil, Iprodione, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate.

Metalaxyl, also known as methyl N-(methoxyacetyl)-N-(2,6-xylyl)-DL-alaninate,  is a systemic fungicide with the chemical formula C15H21NO4.  It is used to control Pythium and Phytophthora in vegetables. It has suffered a resistance problem going back to the 1980s.

Propoxur is a non-systemic insecticide produced from catechol with the chemical formula C11H15NO3. It has a variety of uses from turf, forestry, and agricultural pests to household pests and fleas.

Paclobutrazol (PBZ) is a synthetic triazole compound with the chemical formula C15H20ClN3O. It is used to control plant growth as an antagonist of the plant hormone gibberellin. Through reducing reducing internodal growth, it causes stronger stems, greater root growth, and earlier fruitset. It can also reduce frost sensitivity in plants.

Abamectin is a insecticide with the chemical formulas  C48H72O14 and C47H70O14. It is also used to control fire ant populations. In veterinary cases, it is used to deworm horses as well as an antihelmintic.

Propanil is a contact herbicide with the chemical formula C9H9Cl2NO. It is one of the most widely used herbicides in America. It works as an inhibitor of photosynthesis and CO2 fixation in weeds.

Iprodione is a hydantoin fungicide and nematicide with the chemical formula C13H13Cl2N3O3. It is used on a wide variety of crops that are affected by fungal diseases such as botrytis bunch rot, brown rot, and Sclerotinia.  Approval of using it is different across the world.

Dursban is a highly toxic organophosphate with the chemical formula C9H11Cl3NO3PS. It works through interrupting the electrochemical processes in nerves.  This leads to a build-up of acetylcholine, which leads to paralysis and eventual death.

Pentachlorophenol is a manufactured chemical with the chemical formula C6HCl5O. It is most often used as herbicide, insecticide, fungicide, algaecide, and disinfectant. Exposure to it can cause damage to liver, kidney, blood, lungs, eyes, skin, and mouth. It is classified as a probable human carcinogen.

Fenvalerate is synthetic pyrethroid insecticide with the chemical formula C25H22ClNO3. It is used against a wide range of pests, partially due to it’s moderate mammalian toxicity following short-term and acute exposure. It is the most toxic to bees and fish.  Upon contact, it may irritate skin and eyes.

Metalaxyl (UV), Propoxur, Paclobutrazol, Abamectin, Propanil, Iprodione, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate can be retained and analyzed using the Newcrom B stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a formic acid buffer. Detection is performed using UV.

Condition

Column Newcrom B, 4.6 x 150 mm, 3 µm, 100 A, dual ended
Mobile Phase MeCN/H2O
Buffer Formic Acid
Flow Rate 1.0 ml/min
Detection UV, 260, 270 nm

Description

Class of Compounds Hydrophobic, Herbicide, Pesticide
Analyzing Compounds Metalaxyl (UV), Propoxur, Paclobutrazol, Abamectin, Propanil, Iprodione, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate

Application Column

Newcrom B

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Abamectin
Chlorpyrifos-methyl (Dursban)
Fenvalerate
Iprodione
Metalaxyl (UV)
Paclobutrazol
Pentachlorophenol
Propanil
Propoxur

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of 12 Pesticides on Newcrom B Column

January 24, 2020

HPLC Method for 6-Benzylaminopurine, Metalaxyl (UV), Prochloraz, Paclobutrazol, Propanil, Chlorothalonil, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate, Abamectin, Procymidone, Bifenazate on Newcrom B by SIELC Technologies

 

High Performance Liquid Chromatography (HPLC) Method for Analysis of 6-Benzylaminopurine, Metalaxyl (UV), Prochloraz, Paclobutrazol, Propanil, Chlorothalonil, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate, Abamectin, Procymidone, Bifenazate.

6-Benzylaminopurine is a plant growth regulation compound with the molecular formula C12H11N5. It’s presence in asparagus, for example, leads to deeper color, increased firmness, and a decrease in fibrous hardness. In general, it stimulates cell division and differentiation.

Metalaxyl, also known as methyl N-(methoxyacetyl)-N-(2,6-xylyl)-DL-alaninate,  is a systemic fungicide with the chemical formula C15H21NO4.  It is used to control Pythium and Phytophthora in vegetables. It has suffered a resistance problem going back to the 1980s.

Prochloraz is an imidazole fungicide with the chemical formula C15H16Cl3N3O2. It is used widely across Europe, Asia, South America, and Australia, but is not registered for use in the United States. It works as an inhibitor of the enzyme lanosterol 14α-demethylase.

Paclobutrazol (PBZ) is a synthetic triazole compound with the chemical formula C15H20ClN3O. It is used to control plant growth as an antagonist of the plant hormone gibberellin. Through reducing reducing internodal growth, it causes stronger stems, greater root growth, and earlier fruitset. It can also reduce frost sensitivity in plants.

Procymidone is a pesticide and fungicide with the chemical formula  C13H11Cl2NO2. It is typically used to kill unwanted ferns, nettles, and fungi in lupins, grapes, stone fruit, and strawberries.

Propanil is a contact herbicide with the chemical formula C9H9Cl2NO. It is one of the most widely used herbicides in America. It works as an inhibitor of photosynthesis and CO2 fixation in weeds.

Chlorothalonil is a compound with a variety of uses as a fungicide, wood protectant, pesticide, and acaricide. It is used predominantly on peanuts, potatoes, and tomatoes. Outside of agriculture, it is also used in paints, resins, emulsions, and coatings. It’s chemical formula is C8Cl4N2.

Abamectin is a insecticide with the chemical formulas  C48H72O14 and C47H70O14. It is also used to control fire ant populations. In veterinary cases, it is used to deworm horses as well as an antihelmintic.

Bifenazate is pesticide with the chemical formula C17H20N2O3. It is typically used to control a large variety of mite pests in plants in various settings. It works through modulating GABA receptors and inhibiting complex III of the mitochondrial electron transport chain.

Dursban is a highly toxic organophosphate with the chemical formula C9H11Cl3NO3PS. It works through interrupting the electrochemical processes in nerves.  This leads to a build-up of acetylcholine, which leads to paralysis and eventual death.

Pentachlorophenol is a manufactured chemical with the chemical formula C6HCl5O. It is most often used as herbicide, insecticide, fungicide, algaecide, and disinfectant. Exposure to it can cause damage to liver, kidney, blood, lungs, eyes, skin, and mouth. It is classified as a probable human carcinogen.

Fenvalerate is synthetic pyrethroid insecticide with the chemical formula C25H22ClNO3. It is used against a wide range of pests, partially due to it’s moderate mammalian toxicity following short-term and acute exposure. It is the most toxic to bees and fish.  Upon contact, it may irritate skin and eyes.

6-Benzylaminopurine, Metalaxyl (UV), Prochloraz, Paclobutrazol, Propanil, Chlorothalonil, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate, Abamectin, Procymidone, Bifenazate can be retained and analyzed using the Newcrom B stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a formic acid buffer. Detection is performed using UV.

Condition

Column Newcrom B, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN/H2O
Buffer Formic Acid
Flow Rate 1.0 ml/min
Detection UV, 260 nm

Description

Class of Compounds Hydrophobic, Herbicide, Pesticide
Analyzing Compounds 6-Benzylaminopurine, Metalaxyl (UV), Prochloraz, Paclobutrazol, Propanil, Chlorothalonil, Chlorpyrifos-methyl (Dursban), Pentachlorophenol, Fenvalerate, Abamectin, Procymidone, Bifenazate

Application Column

Newcrom B

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
6-Benzylaminopurine
Abamectin
Bifenazate
Chlorothalonil
Chlorpyrifos-methyl (Dursban)
Fenvalerate
Metalaxyl (UV)
Paclobutrazol
Pentachlorophenol
Prochloraz
Procymidone
Propanil

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Pentachlorophenol on Newcrom R1 HPLC column

February 19, 2018
Separation of Pentachlorophenol on Newcrom C18 HPLC column

Pentachlorophenol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Pentachlorophenol
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.