HPLC Method for Analysis of Venlafaxine on Chromni Column

HPLC Method for Venlafaxine on Chromni™ by SIELC Technologies


High Performance Liquid Chromatography (HPLC) Method for Analysis of Venlafaxine

Venlafaxine serotonin-norepinephrine reuptake inhibitor (SNRI) with the molecular formula C17H27NO2.

Properties:
Appearance: Variety of tablets and capsules as determined by the distributor

Molecular weight: ~277.402 g/mol

Solubility: Soluble in water.

Uses: Medication for treating Major Depressive Disorder

Venlafaxine can be retained and analyzed using the Chromni™ stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water, acetonitrile (MeCN). Detection is performed using UV.

ColumnChromni™, 4.6 x 150 mm, 3 µm, 100 A, dual ended
Mobile PhaseMeCN – 15%
BufferPhosphoric Acid
Flow Rate1.0 ml/min
DetectionUV 275 nm

Class of Compoundstertiary amino
Analyzing CompoundsVenlafaxine

Application Column

Chromni™

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Venlafaxine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.