Delafloxacin

Delafloxacin

CAS Number189279-58-1
Molecular FormulaC18H12ClF3N4O4
Molecular Weight440.8
InChI KeyDYDCPNMLZGFQTM-UHFFFAOYSA-N
LogP2.7
Synonyms
  • WQ-3034
  • ABT492
  • Abt 492
  • RX-3341
  • 1-(6-AMINO-3,5-DIFLUOROPYRIDIN-2-YL)-8-CHLORO-6-FLUORO-7-(3-HYDROXYAZETIDIN-1-YL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
  • 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid
  • UNII-6315412YVF
  • 6315412YVF
  • 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-
  • 1-(6-amino-3,5-difluoro-2-pyridyl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-quinoline-3-carboxylic acid
  • Delafloxacin [USAN:INN]
  • Delafloxacinum
  • Quofenix
  • Delafloxacin (USAN)

Applications:

Uv-Vis Spectrum of Delafloxacin

March 5, 2026

Access the UV-Vis Spectrum SIELC Library

If you are looking for optimized HPLC method to analyze Delafloxacin check our HPLC Applications library

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.

Application Analytes:
Delafloxacin
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Determination of Delafloxacin on Primesep 100 Column

September 21, 2022

HPLC Method for Delafloxacin on Primesep 100 by SIELC Technologies

HPLC Method for Determination of Delafloxacin on Primesep 100 Column by SIELC Technologies
HPLC Method for Determination of Delafloxacin on Primesep 100 Column by SIELC Technologies

Delafloxacin, also known as Baxdela, is a popular antibiotic with the chemical formula C18H12ClF3N4O4. It is used to treat skin infections from both gram-positive and gram-negative bacteria.

Delafloxacin can be retained and analyzed on a Primesep 100 mixed-mode stationary phase column using an isocratic analytical method with a simple isocratic mobile phase of water, Acetonitrile (MeCN), and a sulfuric acid (H2SO4) buffer.  This analysis method can be UV detected at 290 nm with high resolution and peak symmetry.

Condition
Column Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN – 40%
Buffer H2SO4 – 0.2%
Flow Rate 1.0 ml/min
Detection UV 290 nm

Description
Class of Compounds Drug
Analyzing Compounds Delafloxacin

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Delafloxacin
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.