Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester

Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester structural formula

CAS Number80-55-7
Molecular FormulaC6H12O3
Molecular Weight132.159
InChI KeyGFUIDHWFLMPAGY-UHFFFAOYSA-N
LogP0.465
Synonyms
  • Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester
  • Ethyl 2-hydroxy-2-methylpropanoate
  • 80-55-7
  • 4-03-00-00783
  • BRN 0878308
  • EINECS 201-290-3
  • Ethyl alpha-hydroxyisobutyrate
  • Ethyl 2-hydroxyisobutyrate
  • Ethyl 2-hydroxy-2-methylpropanoate
  • Ethyl 2-methyllactate
  • 2-Methyllactic acid ethyl ester
  • NSC 4667

Applications:

Separation of Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester on Newcrom R1 HPLC column

February 16, 2018
Separation of Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester on Newcrom C18 HPLC column

Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.