Progesterone

Progesterone structural formula

CAS Number57-83-0
Molecular FormulaC21H30O2
Molecular Weight314.469
InChI KeyRJKFOVLPORLFTN-LEKSSAKUSA-N
LogP3.87
Synonyms
  • Progesterone
  • Pregn-4-ene-3,20-dione
  • 57-83-0
  • P
  • Pregn-4-ene-3,20-dione
  • Agolutin
  • Bio-luton
  • Corlutin
  • Corlutina
  • Corluvite
  • Corporin
  • Corpus luteum hormone
  • Crinone
  • Cyclogest
  • Duraprogen
  • Endometrin
  • Flavolutan
  • Fologenon
  • Gesterol
  • Gestiron
  • Gestone
  • Gestormone
  • Gestron
  • Glanducorpin
  • Gynlutin
  • Gynolutone
  • Hormoflaveine
  • Hormoluton
  • Lipo-Lutin
  • Lucorteum Sol
  • Lugesteron
  • Luteal Hormone
  • Luteinique
  • Luteocrin normale
  • Luteodyn
  • Luteogan
  • Luteohormone
  • Luteopur
  • Luteosan
  • Luteostab
  • Luteovis
  • Lutidon
  • Lutociclina
  • Lutocuclin M
  • Lutocyclin
  • Lutocyclin M
  • Lutocylin
  • Lutoform
  • Lutogyl
  • Lutromone
  • Nalutron
  • NSC 64377
  • NSC 9704
  • Percutacrine Luteinique
  • Piaponon
  • Primolut
  • Prochieve
  • Progeffik
  • Progekan
  • Progestan
  • Progestasert
  • Progesterol
  • Progesteron
  • progesterona
  • Progestin
  • Progestogel
  • Progestol
  • Progestone
  • Progestron
  • Prolets
  • Prolidon
  • Proluton
  • Prometrium
  • Prontogest
  • Protormone
  • Syngesterone
  • Syngestrets
  • Syntolutan
  • Utrogest
  • Utrogestan
  • Vitarrine
  • ?4-Pregnene-3,20-dione
  • EINECS 200-350-6
  • 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione
  • 6alpha-Methylpregn-4-en-17alpha-ol-3,20-dione
  • NSC-9704
  • 4-Pregnene-3,20-dione
  • Pregn-4-ene-3,20-dione, 17alpha-hydroxy-6alpha-methyl-
  • Projestaject
  • UNII-4G7DS2Q64Y
  • (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
  • (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • (8S,9S,10R,13S,14S,17S)-17-ethanoyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • 17a-Progesterone
  • 17alpha-progesterone
  • 3,20-Pregnene-4
  • 4-Pregnen-3,20-dione
  • Akrolutin
  • CIDR
  • Colprosterone
  • Crinone progesterone gel
  • Curretab
  • Cyclogesterin
  • D4-Pregnene-3,20-dione
  • Delalutin
  • Delta(4)-pregnene-3,20-dione
  • Estima
  • Gelbkoerperhormon
  • Gesterol 100
  • Gesterol 50
  • Glanducorpin
  • Gynoluton
  • Hydroxyprogesterone Caproate
  • Hydroxyprogesterone Caproic acid
  • Lingusorbs
  • Lucorteum
  • Luteal hormone
  • Luteol
  • Luteum
  • Lutex
  • Lutocylol
  • Lutoform
  • Lutren
  • MPA
  • Membrettes
  • Methylpregnone
  • Percutacrine
  • Pranone
  • Pregn-4-en-3,20-dione
  • Pregnene-3,20-dione
  • Pregnenedione
  • Primolut
  • Progesteronum
  • Progeston
  • Progestosol
  • Progestronol
  • Projestaject
  • Prolutin
  • Prolutone
  • Synovex S
  • beta-Progesterone
  • delta(Sup 4)-Pregnene-3,20-dione
  • 257630-50-5
  • 753497-20-0
  • 8012-32-6
  • 8023-13-0

Applications:

Separation of Progesterone on Newcrom R1 HPLC column

February 16, 2018
Separation of Progesterone on Newcrom C18 HPLC column

Progesterone is a female sex hormone along with estrogen. It is involved in regulating menstrual cycle, pregnancy, and embryogenesis. Furan can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particle columns are available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation of impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Progesterone
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.