Pilocarpine hydrochloride

Pilocarpine hydrochloride structural formula

CAS Number54-71-7
Molecular FormulaC11H17ClN2O2
Molecular Weight244.721
InChI KeyRNAICSBVACLLGM-GNAZCLTHSA-N
LogP0.187
Synonyms
  • Pilocarpine hydrochloride
  • (3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one--hydrogen chloride (1/1)
  • 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S,4R)-, hydrochloride (1:1)
  • 54-71-7
  • PILO
  • 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S,4R)-
  • (+)-Pilocarpine hydrochloride
  • 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, hydrochloride (1:1), (3S,4R)-
  • 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S-cis)-
  • Adsorbocarpine
  • Almocarpine
  • Isopto Carpine
  • NSC 5746
  • Pilocar
  • Pilocar SMP
  • Pilocarpal
  • pilocarpina, clorhidrato
  • Pilocarpine chloride
  • PILOCARPINE HCL
  • Pilocarpine muriate
  • Pilocarpine, chlorhydrate
  • Pilocarpine, monohydrochloride
  • Pilocarpinhydrochlorid
  • Pilocarpinium chloride
  • Pilocel
  • Pilovisc
  • Salagen
  • Vistacarpin N
  • Ami-pilo
  • Amistura P
  • EINECS 200-212-5
  • Isopto-carpine
  • MI-Pilo Ophth Sol
  • Mistura P
  • Pilocarpine, hydrochloride
  • Pilocarpine monohydrochloride
  • Pilokarpin monohydrochloride
  • Pilomiotin
  • Sno pilo
  • Spersacarpine hydrochloride
  • Pilopine HS
  • UNII-0WW6D218XJ

Applications:

Separation of Pilocarpine hydrochloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Pilocarpine hydrochloride on Newcrom C18 HPLC column

Pilocarpine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Pilocarpine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.