Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt

Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt structural formula

CAS Number575-75-7
Molecular FormulaC9H13NNaO2P
Molecular Weight221.172
  • Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt
  • Sodium [4-(dimethylamino)-2-methylphenyl]phosphinate
  • Phosphinic acid, P-[4-(dimethylamino)-2-methylphenyl]-, sodium salt (1:1)
  • 575-75-7
  • EINECS 209-391-4
  • UNII-6139240O1E


Separation of Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt on Newcrom R1 HPLC column

February 16, 2018
Separation of Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt on Newcrom C18 HPLC column

Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Phosphinic acid, [4-(dimethylamino)-2-methylphenyl]-, sodium salt
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.