Lutein

Lutein structural formula

CAS Number127-40-2
Molecular FormulaC40H56O2
Molecular Weight568.886
InChI KeyKBPHJBAIARWVSC-RGZFRNHPSA-N
LogP10.8
Synonyms
  • Lutein
  • (3R,3'R,6R)-4,5-Didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol
  • beta,beta-Carotene-3,3'-diol, 4,5-didehydro-5,6-dihydro-, (3R,3'R,6R)-
  • 127-40-2
  • ?,?-Carotene-3,3'-diol, (3R,3'R,6'R)-
  • (3R,3'R,6'R)-Lutein
  • (3R,3'R,6'R)-?,?-Carotene-3,3'-diol
  • (all-E)-Lutein
  • 6'-Hydro-4',5'-dehydro-?-carotene-3,3'-diol
  • all-trans-(+)-Xanthophyll
  • all-trans-Lutein
  • all-trans-Xanthophyll
  • FloraGLO
  • Lutein A
  • Luteine
  • trans-Lutein
  • Vegetable lutein
  • Vegetable luteol
  • Xanthophyll
  • ?,]-caroteno-3,3'-diol
  • ?,?-Carotene-3,3'-diol
  • ?,?-Carotin-3,3'-diol
  • EINECS 204-840-0
  • Lutein, all-trans-
  • NSC 59193
  • Xanthophyll, all-trans-(+)-
  • UNII-X72A60C9MT
  • (4R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-3,5,5-trimethylcyclohex-2-en-1-ol
  • 3,3'-Dihydroxy-alpha-carotene
  • Bo-Xan
  • E 161b
  • Lutein ester
  • beta,epsilon-Carotene-3,3'-diol
  • 1407-74-5
  • 148124-35-0
  • 25312-96-3
  • 28368-07-2
  • 34026-62-5
  • 34445-91-5

Applications:

Separation of Lutein on Newcrom R1 HPLC column

May 16, 2018
Separation of Lutein on Newcrom R1 HPLC column

Lutein is a yellow compound found in plants to modulate the amount of light hitting the chlorophyll molecule. In the human body, lutein is found in the eye, although its exact role is unknown. Lutein can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particle columns are available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation of impurities in preparative separation. It also suitable for pharmacokinetics.
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Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Lutein
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.