Isopropyl 2-cyanoacrylate

Isopropyl 2-cyanoacrylate structural formula

CAS Number10586-17-1
Molecular FormulaC7H9NO2
Molecular Weight139.155
InChI KeySQGOMFWCSGKGEP-UHFFFAOYSA-N
LogP1.08
Synonyms
  • Isopropyl 2-cyanoacrylate
  • Propan-2-yl 2-cyanoprop-2-enoate
  • 2-Propenoic acid, 2-cyano-, 1-methylethyl ester
  • 10586-17-1
  • Acrylic acid, 2-cyano-, isopropyl ester
  • EINECS 234-188-2
  • Isopropyl alpha-cyanoacrylate
  • UNII-I03LI0901Y

Applications:

Separation of Isopropyl 2-cyanoacrylate on Newcrom R1 HPLC column

February 19, 2018
Separation of Isopropyl 2-cyanoacrylate on Newcrom C18 HPLC column

Isopropyl 2-cyanoacrylate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Isopropyl 2-cyanoacrylate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.