HPLC Method for Analysis of Venlafaxine on Primesep 100 Column

HPLC Method for Venlafaxine on Primesep 100 by SIELC Technologies


High Performance Liquid Chromatography (HPLC) Method for Analysis of Venlafaxine

Venlafaxine is an organic compound with the molecular formula C17H27NO2.

Properties:
Appearance: Typically a white to off-white crystalline solid.

Molecular weight: ~277.4 g/mol

Solubility: Soluble in organic solvents.

Uses: A type of antidepressant. It is believed to work by increasing levels of serotonin and norepinephrine in the brain.

Venlafaxine can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water, acetonitrile (MeCN), and sulfuric acid. Detection is performed using UV at 200 nm.

ColumnPrimesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile PhaseMeCN – 80%
BufferH2SO4 – 0.1%
DetectionUV 200 nm

Class of CompoundsDrug
Analyzing CompoundsVenlafaxine

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Venlafaxine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.