HPLC Method for Analysis of Losartan on Newcrom R1 Column

HPLC Method for Analysis of Losartan on Newcrom R1 Column by SIELC Technologies

Separation type: Liquid Chromatography Reversed-phase

HPLC Method for Analysis of Losartan on Newcrom R1 Column by SIELC Technologies

Losartan is a medication that belongs to a class of drugs known as angiotensin II receptor blockers (ARBs).

  • Losartan is primarily used to treat high blood pressure (hypertension) and certain other conditions related to the heart.
  • It works by blocking the action of angiotensin II, a substance in the body that narrows blood vessels and releases hormones that can raise blood pressure.

Losartan can be retained, and analyzed on a reversed-phase Newcrom R1 column with a mobile phase consisting of water, Acetonitrile (MeCN), and sulfuric acid. This analytical method can be detected with high resolution and peak symmetry at a wavelength of 200 nm using UV detection

High Performance Liquid Chromatography (HPLC) Method for Analyses of Losartan on Newcrom R1 Column by SIELC Technologies

Condition

ColumnNewcrom R1, 3.2 x 100 mm, 5 µm, 100 A
Mobile PhaseMeCN/H2O – 30/70%,
BufferH2SO4 – 0.1%
Flow Rate0.5 ml/min
DetectionUV 200 nm

Description

Class of CompoundsDiphenyl ethers
Analyzing CompoundsLosartan

Application Column

Newcrom R1

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
Losartan
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.