HPLC Determination of Cefadroxil on Primesep 100 Column

HPLC Method for Cefadroxil on Primesep 100 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis Cefadroxil

Cefadroxil is a cephalosporin antibiotic used to treat many different types of infections caused by bacteria. Some infections that cephalosporins can be used to treat include respiratory tract infections, otitis media (middle ear infection), strep throat, skin infections, skin structure infections, bone infections, and urinary tract infections

Cefadroxil can be retained on the Newcrom BH mixed-mode column using an isocratic analytical method with a simple mobile phase of water, acetonitrile (MeCN, ACN), and sulphuric acid (H2SO4) buffer. The analysis method can be UV detected at 270 nm.

Condition
Column Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 15/85%
Buffer H2SO4 – 0.5%
Flow Rate 1.0  ml/min
Detection UV 270 nm

 

Description
Class of Compounds
  Drug
Analyzing Compounds Cefadroxil

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Cefadroxil
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.