| CAS Number | 108-55-4 |
|---|---|
| Molecular Formula | C5H6O3 |
| Molecular Weight | 114.100 |
| InChI Key | VANNPISTIUFMLH-UHFFFAOYSA-N |
| LogP | -0.207 |
| Synonyms |
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Applications:
HPLC Method for Analysis of Glutaric Anhydride on Newcrom R1 Column
June 13, 2022
Separation type: Liquid Chromatography Reverse Phase.
High Performance Liquid Chromatography (HPLC) Method for Analysis of Glutaric Anhydride
Glutaric Anhydride is a common intermediate used in the production of pharmaceuticals, corrosion inhibitors, and polymers. Glutaric Anhydride can be separated and analyzed on a Newcrom R1 reverse-phase column using a simple gradient analytical method with a mobile phase consisting of just Acetonitrile (MeCN) and water (with no ionic modifier). This analysis method can be UV detected at 220 nm with high resolution and peak symmetry.
| Column | Newcrom R1, 4.6×150 mm, 100A |
| Mobile Phase | MeCN – 10% |
| Buffer | No |
| Flow Rate | 10 ml/min |
| Detection | UV 220 nm |
| Class of Compounds | Anhydride |
| Analyzing Compounds | Glutaric Anhydride |
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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Separation of Glutaric anhydride on Newcrom R1 HPLC column
February 16, 2018
Glutaric anhydride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options