Glutaric anhydride

Glutaric anhydride structural formula

CAS Number108-55-4
Molecular FormulaC5H6O3
Molecular Weight114.100
InChI KeyVANNPISTIUFMLH-UHFFFAOYSA-N
LogP-0.207
Synonyms
  • Glutaric anhydride
  • Oxane-2,6-dione
  • 2H-Pyran-2,6(3H)-dione, dihydro-
  • 108-55-4
  • 2H-Pyran-2,6(3H)-dione, dihydro-
  • 5-17-11-00009
  • anhidrido glutarico
  • Anhydride glutarique
  • Dihydro-2H-pyran-2,6(3H)-dione
  • Dihydro-3H-pyran-2,6-dione
  • Dihydropyran-2,6-dione
  • Glutaric acid anhydride
  • GLUTARSAEUREANHYDRID
  • Glutarsaureanhydrid
  • NSC 16640
  • Pentanedioic acid anhydride
  • Pentanedioic anhydride
  • Pyroglutaric acid
  • BRN 0110051
  • EINECS 203-593-6
  • Anhydrid kyseliny glutarove

Applications:

HPLC Method for Analysis of Glutaric Anhydride on Newcrom R1 Column

June 13, 2022

Separation type: Liquid Chromatography Reverse Phase.


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HPLC Method for Analysis of Glutaric Anhydride on Newcrom R1 Column

High Performance Liquid Chromatography (HPLC) Method for Analysis of Glutaric Anhydride

Glutaric Anhydride is a common intermediate used in the production of pharmaceuticals, corrosion inhibitors, and polymers. Glutaric Anhydride can be separated and analyzed on a Newcrom R1 reverse-phase column using a simple gradient analytical method with a mobile phase consisting of just Acetonitrile (MeCN) and water (with no ionic modifier). This analysis method can be UV detected at 220 nm with high resolution and peak symmetry.

ColumnNewcrom R1, 4.6 x 150 mm, 3 µm, 100 A
Mobile PhaseMeCN – 10%
BufferNo
Flow Rate1.0 ml/min
DetectionUV 220 nm
Class of Compounds Anhydride
Analyzing CompoundsGlutaric Anhydride

Application Column

Newcrom R1

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A

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Application Analytes:
Glutaric anhydride
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Glutaric anhydride on Newcrom R1 HPLC column

February 16, 2018
Separation of Glutaric anhydride on Newcrom C18 HPLC column

Glutaric anhydride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Glutaric anhydride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.